Gut Microbiota: The Missing Link in Obesity Induced Nonalcoholic Liver Disease
Journal Title: IOSR Journals (IOSR Journal of Electrical and Electronics Engineering) - Year 2017, Vol 12, Issue 1
Abstract
Background and objective: Recent research has elucidated a close association between intestinal microbiota, obesity, insulin resistance and nonalcoholic hepatic injury. Various studies have also indicated an increase in hepatic marker enzymes in obesity. Hence, this study aims to evaluate the association of gut microbiota with obesity, insulin resistance and hepatic marker enzymes. Material and Method: This case-control study was conducted during March 2015 to October 2016 At S.C.B Medical College, Cuttack, Odisha. The study included 186 subjects (86 irritable bowel syndrome patients as per the Rome III criteria and hundred matched controls). Plasma fasting glucose, serum lipid profile, hepatic marker enzymes were analysed by commercial kits adapted to automated clinical chemistry analyser and serum fasting insulin was estimated by kits adapted to Lisa Scan. Observation: Compared to controls the Irritable bowel syndrome patients had significantly higher Body mass index (20.9± 5.6 vs 30.1±0.22), Waist-hip ratio (0.9 ± 0.11 vs 1.02 ± 0.06), lipid profile, hepatic marker enzymes and insulin resistance. Conclusion: IBS patients were obese, and exhibited dyslipidemia, insulin resistance, elevated hepatic enzymes suggesting development of NAFLD.
Authors and Affiliations
Roma Rattan, Purnendu Panda2, Srikrushna Mahapatra3
Keywords
Related Articles
- EP ID EP387214
- DOI 10.9790/3008-1201010811
- Views 148
- Downloads 0
Automatic water level controller using NOR Gates
Automatic water level controller circuit is a simple electronics project. It can automatically switch ON and OFF the domestic water pump set depending on the tank water level. You can implement this motor driver circuit...
Substation Earthing Design
Successful operation of entire power system depends to a considerable extent on efficient and satisfactory performance of substations. Hence substations in general can be considered as heart of overall power system. In a...
Representation of New Electrical Load Tariff to Be Implemented in Future
The demand for electricity in India is increasing every day. As per demand utility is required to generate, transmit and distribute electricity among different consumers. The cost incurred by utility for this purpose is...
UAV Heading Control in Windy and Turbulent Conditions Using Reinforcement Learning
Due to the high non-linearity and coupling of a system model in an Unmanned Aerial Vehicle, UAV, the control of the heading has been a challenging task especially under windy and turbulent conditions. In this paper an on...
Harmonics Currents Cancelation by Three-Phase 4-wire Hybrid Active Power Filter with Split Capacitors and STF
The quality of electrical power is the major important goal of all researchers. In utility power system it has been observed that harmonics build a major role in reducing the quality power. These harmonics caused by nonl...