Haematological Parameters in sickle cell anemia patients a hospital based observational study at tertiary care centre in rural area of Vidarbha Region
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 4
Abstract
Sickle cell disease is a genetic abnormality involving the haemoglobin. Sickle Cell Anaemia is a hereditary haemolytic anaemia, predominantly seen amongst various tribal populations of India. Although, it is primarily a red cell disorders, the white blood cells and platelets are also affected by the mutation. This study aims to provide baseline haematological values in sickle cell disease patients in steady state and crisis events. A hospital based observational study is carried out at tertiary care centre in tribal area of vidarbha region. A consecutive 100 hospitalized patients and patients who attended the OPD satisfying the selection criteria were recruited. About 4.5mls of blood sample was collected from each participant for full blood count analysis. Homozygous sickle cell disease patients have lower values of red cell parameters, but higher values of white cell and platelets counts.
Authors and Affiliations
Vikas R Yedshikar, Hitendra J Khandekar, Waman K Raut, Balawant Kowe
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