HBV infection among blood donors from 18 domestic blood stations of prefecture-level cities

Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 2

Abstract

Objective To analyze the hepatitis B virus (HBV) infection data of blood donors from 18 domestic blood stations, so as to investigate the HBV infection situation of blood donors. Methods The positive rate of HBV and its distribution characteristics of regions, the percentage of HBsAg+ ELISA in first-time vs repeated blood donors, and the percentage of HBsAg-/HBV DNA+ blood donors of 18 domestic blood stations during 2017 to 2020 were collected from the Working Platform for Practice Comparison of Blood Centers, and the HBV infection among blood donors were statistically analyzed. Results From 2017 to 2020, the positive rate of HBV in blood donors among 18 domestic blood stations was 13.48/10 000-144.02/10 000, with the average HBV positive rate in eastern, central and western region at 26.14/10 000, 51.98/10 000 and 41.00/10 000, respectively. The HBsAg+ rate by ELISA among first-time and repeated blood donors was 14.55/10 000-305.39/10 000 vs 1.04/10 000-87.43/10 000 The HBsAg-/HBV DNA+ yield was 1.80/10 000-35.31/10 000. Conclusion The distribution of HBV infection in blood donors has regional characteristics, and HBV prevalence was low in repeated blood donors. HBsAg ELISA combined with HBV DNA detection can better ensure blood safety.

Authors and Affiliations

Dingding WANG, Youhua SHEN, Jianling ZHONG, Hui ZHANG, Zhibin TIAN, Lin BAO, Huixia ZHAO, Jian ZHANG, Peng WANG, Yanqin HE, Wei ZHANG, Li LI, Hao LI, Dexu CHU, Ying WANG, Xin ZHANG, Shouguang XU, Min HUANG, Yan QIU

Keywords

Related Articles

Performance verification experiment for enzyme-linked immunosorbent assay in blood screening laboratory

Objective To verificate the performance of enzyme-linked immunosorbent assay (ELISA) in blood screening laboratory. Methods The repeatability, precision, sensitivity, specificity, compliance, detection limit and anti-int...

Study on the extensibility of platelet donor gene database in Shaanxi

Objective To analyze the commonality and characteristics between voluntary blood donors and hematopoietic stem cell donors in this region, and explore the potential for integration and development between China Marrow Do...

Genetic analysis of a weak D type61 sample from a blood donor, Jiangyin

Objective To genetically analyze the Del sample from a blood donor in Jiangyin and make clear the molecular basis of the serological phenotype. Methods The EDTA anticoagulant blood were collected: buffy coat were used fo...

Effects of GYP mRNA alternative splicing on cell surface localization of MNS blood group glycoprotein GPA and GPB

Objective To analyze the polymorphisms of GYPA and GYPB mRNA spliceosomes associated with MNS blood group, and to explore the mechanism of subcellular localization of GPA and GPB protein isomerism encoded by various spli...

Clinical application progress of granulocyte transfusion

Granulocyte is granular leukocytes in blood, which play an important role in anti-infection treatment and cancer-killing activity. In clinical, allogeneic granulocyte transfusion can be applied for anti-infection treatme...

Download PDF file
  • EP ID EP738493
  • DOI 10.13303/j.cjbt.issn.1004-549x.2023.02.019
  • Views 4
  • Downloads 0

How To Cite

Dingding WANG, Youhua SHEN, Jianling ZHONG, Hui ZHANG, Zhibin TIAN, Lin BAO, Huixia ZHAO, Jian ZHANG, Peng WANG, Yanqin HE, Wei ZHANG, Li LI, Hao LI, Dexu CHU, Ying WANG, Xin ZHANG, Shouguang XU, Min HUANG, Yan QIU (2023). HBV infection among blood donors from 18 domestic blood stations of prefecture-level cities. Chinese Journal of Blood Transfusion, 36(2), -. https://europub.co.uk/articles/-A-738493