HDL and blood glucose levels in schizophrenia: A comparative study among untreated, treated and their first degree relatives
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 10
Abstract
Objective: to compare any differences in the hdl levels and blood glucose levels among untreated schizophrenia patients, treated schizophrenia patients and their first degree relatives. Methodology: the study is conducted among untreated schizophrenia patients, treated schizophrenia patients and their first degree relatives who came to Mamata general hospital, khammam. Total study sample consists of 90 out of which there are 30 treated schizophrenic patients, 30 untreated schizophrenic patients and 30 first degree relatives of either group who were randomly selected. estimation of hdl levels by peg precipitation method, estimation of blood glucose by glucose oxidase/peroxidase method Results: In present study we observed that mean fbs was significantly higher in treated schizophrenics compared to untreated schizophrenics and fdr. There was significantly higher rate of impaired fasting glucose in patients treated with anti-psychotics when compared to drug naive and first degree relatives. in present study we observed mean hdl was significantly lower in treated schizophrenics compared to untreated schizophrenics and fdr. mean hdl was significantly lower in untreated schizophrenics compared to fdr. There was significantly higher rate of low hdl in patients treated with anti-psychotics when compared to drug naive and first degree relatives. Conclusion: use of second generation anti-psychotics in schizophrenia patients significantly affects lipid profile and glucose metabolism.
Authors and Affiliations
B Ramakrishna, Murali Krishna V, Vijay Kumar M, Raghuram Macharapu
Keywords
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