Heart failure with preserved ejection fraction in rheumatoid arthritis and the role of interleukin-6 blockade
Journal Title: International Journal of Clinical Rheumatology - Year 2017, Vol 12, Issue 1
Abstract
There is growing evidence on the potential benefits of tocilizumab on the cardiovascular system in Rheumatoid Arthritis (RA) patients. We discuss a case of active RA and refractory Heart Failure with Preserved Ejection Fraction (HFpEF) that has shown dramatic improvement in her articular and cardiac symptoms. This report gives some evidence that tocilizumab could be safely used in RA patients with HFpEF and justify future research on interleukin-6 blockade in heart failure in general.
Authors and Affiliations
Mohammed Q Omair, Rashid AlBallaa, Eman Alqurtas, Waleed Al-Habeeb
An observational study of treatment outcome in cutaneous systemic sclerosis
Objective: An observational method was used for estimation of the effectiveness of different current treatment regimens on skin thickening of PSS. Method: 34 patients of scleroderma were treated with cyclophosphamide-MMF...
Antiphospholipid antibodies and single nucleotide polymorphisms in patients with venous ulcer in the population of Latvia
Background: Chronic venous insufficiency (CVI) may lead to leg ulceration (CVI stage C6) (Nicolaides A.N. et al., 2000). Some authors published that genetic risk factors are observed more frequently in patients with CVI...
Hyperuricemia as an independent predictor and prognostic factor in the development of lupus nephritis
Background: Lupus nephritis (LN) can increase morbidity and mortality risk in systemic lupus erythematosus (SLE) and 25% of the patients with LN will advance to end-stage renal disease. Objective: To evaluate if hyperuri...
Association of weight loss with improved disease activity in patients with rheumatoid arthritis: A retrospective analysis using electronic medical record data
Background: Objective: To evaluate the association between weight loss and rheumatoid arthritis (RA) disease activity. Methods: We conducted a retrospective cohort study of RA patients seen at routine clinic visits at a...
Chronic recurrent multifocal osteomyelitis - case report of two patients and review of literature
Background: Chronic Recurrent Multifocal Osteomyelitis (CRMO) is an autoinflammatory skeletal disease characterized by unifocal or multifocal nonbacterial inflammatory bone lesions in the metaphysis of long bones. Common...