Hedgehog Inhibitors are Effective Treatment for Basal Cell Cancer Recurrence
Journal Title: Journal of Oncology and Cancer Research - Year 2018, Vol 2, Issue 1
Abstract
The hedgehog signaling pathway is one of the major regulators of cell growth and differentiation during embryogenesis. Mutation of some component of hedgehog pathway is common in cancers, especially in basal cell carcinoma (BCC) and Medulloblastoma. Hedgehog inhibitors have recently emerged as a novel treatment for BCC with specific indications and overall clinical benefit. BCC is one of the most common cancers in the United States, comprising approximately 80% of non-melanoma skin cancers. We present a case of an 88 year old female diagnosed with advanced extensive recurrent BCC of scalp whose lesions improved significantly after treatment with Vismodegib despite years of prior neglect.
Authors and Affiliations
Hossein Akhondi
Keywords
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- EP ID EP274757
- DOI 10.28967/jocr.2018.01.18002
- Views 110
- Downloads 0
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