Helicobacter pylori infection among the adults of Vinnytsya region, patients with nonatrophic and atrophic chronic gastritis
Journal Title: Сучасна гастроентерологія - Year 2018, Vol 0, Issue 5
Abstract
Objective — to assess the degree of Helicobacter pylori infection among the adult patients with chronic gastritis (CG) and its relationship with atrophic changes in the gastric mucosa. Materials and methods. The examinations involved 325 patients suffered from chronic gastritis (214 male and 111 female), from them 188 patients with nonatrophic CG and 137 patients with atrophic CG). The control group consisted of 40 persons (18 female and 22 male) without history of gastrointestinal pathology. Results. The frequency of helicobacteriosis among patients with CG (61.54 %) was significantly higher than in the control group (42.5 %): р = 0.032. The degree of H. pylori infection among patients with non-atrophic (61.17 %) and atrophic (62.04 %) CG did not differ and was significantly higher than in control (p = 0.046 and p = 0.043, respectively). Gender differences in H. pylori infection were not found in the study groups. Conclusions. H. pylori infection is a risk factor for disease in the studied group of adult patients with chronic gastritis: OR = 2.13 (95 % CI: 1.07 — 4.26), р = 0.032. Only the presence of H. pylori infection, without taking into account pathogenicity factors, cannot serve as a prognostic parameter for the development of atrophic changes in the gastric mucosa in patients with chronic gastritis.
Authors and Affiliations
D. S. Sukhan, S. V. Vernyhorodskyi, V. M. Shkarupa
Keywords
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- EP ID EP418326
- DOI 10.30978/MG-2018-5-44
- Views 111
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