Hematological profile in typhoid fever
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2015, Vol 1, Issue 1
Abstract
Introduction: Typhoid fever is an acute infection of the blood and intestinal system caused by the bacterium Salmonella typhi. In India S. typhi and S.paratyphi are the common agents of enteric fever. Complications of these lesions are hemorrhage and intestinal perforation. Carrier state is common and bacilli are found in blood, feces and urine. As there is massive multiplication of bacilli in blood stream, this paper aims to study the frequency and severity of hematological changes in patients of typhoid fever with special reference to thrombocytopenia. Methodology: This study was a hospital based descriptive study conducted on OPD and IPD patients of LLR Hospital Kanpur who presented to Emergency Pathology Lab, GSVM Medical College Kanpur. The study design was cross sectional. Study was designed to include demographics, clinical information and hematological changes observed in each patient of typhoid fever using widal test or positive culture. The data was analyzed to study the changes in hematological parameters in these patients. Result: The study revealed the sex ratio to be almost unity and maximum cases were seen in 11-20 year age group. Thrombocytopenia was observed in a significant 39.7% and leucopenia in 11.6% of cases. Mean PCV was reduced to 29.6% and mean neutropil percentage was reduced to28% and mean lymphocyte percentage of was 59% showed relative lymphocytosis. Conclusion: Typhoid fever causes significant hematological changes which could be helpful in diagnosis. Thrombocytopenia is common in typhoid but this association is not well recognized. Awareness of this associate on could be useful in diagnosis of typoid fever more so in under resourced endemic regions in developing countries
Authors and Affiliations
Kanchan Shrivastava, Shilpa Vahikar, Vandana Mishra
Keywords
Related Articles
- EP ID EP327208
- DOI 10.17511/jopm.2015.i1.04
- Views 115
- Downloads 0
Clinico pathological study of thyroid lesions in a rural tertiary care centre
Objective: Present study is clinic pathological study of thyroid lesions in a rural tertiary care Centre. Thyroid lesions are fairly common world wide and are commonly encountered in clinical practice in rural areas also...
Study of iron deficiency anemia with thrombocytosis in association with serum erythropoietin levels
Aim: To evaluate the correlation of iron deficiency anemia with thrombocytosis in correlation with serum erythropoietin levels. Introduction: Thrombocytosis is a common hematologic finding that can present as an incident...
Effectiveness of a multimedia resource in histopathology practical teaching in medical undergraduates-a comparative study
Introduction: Computer technology is found to be a valuable tool to add to the medical teacher’s tool kit. This study was done to assess whether learning through digitalized images have advantage over conventional method...
Prevalence and antibiotic susceptibility patterns of pseudomonas aeruginosa in urinary tract infections in a Tertiary care hospital, Central Kerala: A retrospective study over 4 years
Background and Objective: Pseudomons aeruginosa (P.aeruginosa) is an important uropathogenthat has shown varied antibiotic susceptibility patterns. This study aims to findout the changing trends in theprevalenceand antib...
A histomorphological study of trichilemmal cysts: a rural hospital experience
Introduction: Among Cystic lesions of skin the most common clinical diagnosis is sebaceous cyst. Cystic lesions of the skin are most commonly encountered in surgical practice. Among these cyst lesions Trichilemmal cysts...