Henoch Schonlein Purpura in Children: Clinical Profile and Renal Involvement
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 4
Abstract
Introduction: Henoch Schonlein Purpura (HSP) is the most common systemic vasculitis in children. The objectives of the present study were to describe the clinical profile, complications and management modalities of children with HSP in North Kerala and also to follow them up for a minimum period of six months after diagnosis with special emphasis on renal involvement Materials and Methods: It is a hospital based descriptive follow-up study conducted at a major tertiary care teaching hospital under government sector in North Kerala. 64 children less than 12 years diagnosed to have HSP according to the European League against Rheumatism criteria were included. The clinical features, laboratory investigations, management and complications of the disease were studied, and all children were followed up for a minimum period of six months. Descriptive statistics was used to analyse the results. Results: The mean age was 7.84± 2.69 years with a male female ratio of 1.06:1. The predominant clinical features of HSP were cutaneous purpura (100%), arthritis (82.8%), abdominal symptoms (70.3%), and renal involvement (23.5%).Six children developed renal involvement two weeks after the onset of rash. 15 children (23.5%) had recurrence during the initial six months. 23 (%)children were treated with steroids Conclusions: Equal sex predilection and relatively lower incidence of renal involvement were seen in the present study. Follow up for more time is needed to identify more incidence of renal involvement. Treatment with steroids did not alter the occurrence of renal involvement or recurrence in this study
Authors and Affiliations
Dr T G Sindhu
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