HEPATIC DYSFUNCTION IN DENGUE FEVER- A PROSPECTIVE STUDY DONE AT A TERTIARY CARE HOSPITAL, SHIMOGA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 1
Abstract
BACKGROUND Dengue is a major health concern, especially in tropical country like India. Hepatic dysfunction in dengue fever is a common feature which complicates the clinical course of the infection and worsen the prognosis. This study was done to assess the frequency and spectrum of liver dysfunction in Dengue infection patients. MATERIALS AND METHODS It was a prospective observational study done in Vaatsalya Hospital, Shimoga, for the duration of 6 months, i.e. from 16/05/2017 to 15/11/2017. All patients attending Vaatsalya Hospital, Shimoga with positive serological tests were included in the study after taking written informed consent. Complete blood count and LFT were done and severity of hepatic dysfunction was based on the extent to which ALT and AST were elevated. RESULTS 100% of patients had elevated AST, 100% patients had elevated AST and 85% patients had elevated ALT. The albumin level was low in 75% patients. Average AST was 316 units/L and average ALT was 156 units/L. CONCLUSION Hepatic involvement in dengue is universal. AST elevation is more common than ALT elevation. Reversal of AST to ALT ratio along with high-grade fever and constitutional symptoms may help in early diagnosis of dengue.
Authors and Affiliations
Malavade Praveen, Girish I
Keywords
Related Articles
- EP ID EP284510
- DOI 10.14260/jemds/2018/13
- Views 70
- Downloads 0
EFFICACY OF PROXIMAL FEMORAL NAIL IN PROXIMAL FEMORAL FRACTURES
BACKGROUND Fractures of the subtrochanteric region of femur can be difficult to treat. This anatomic region experiences the highest tensile and compressive stresses in the human skeleton. The proximal fragment is often q...
HISTOENDOCRINOLOGICAL CHANGES INDUCED BY STRESS IN THYROID GLAND OF ALBINO RATS
BACKGROUND The separation of Psychology from the premises of Biology is purely artificial, as the human psyche lives in dissoluble union with the body. Bodily changes are brought about by mental stimuli and emotions as e...
COMPARATIVE ASSESSMENT OF THE AREA OF SEALER VOIDS IN SINGLE-CONE OBTURATION DONE WITH ENDOSEAL MTA, AH PLUS AND PULPDENT SEALER
BACKGROUND Obturation voids have a potential to allow leakage through the sealer mass. Single cone obturation technique is more prone to have voids, as the volume of sealer used is larger as compared to other techniques....
A CLINICO-AETIOLOGICAL STUDY OF CASES OF ERYTHRODERMA ATTENDING TERTIARY CARE HOSPITAL IN NORTH-EAST INDIA
BACKGROUND Erythroderma is the term used for any inflammatory skin disease that affects more than 90% of the body surface area.1 It has many underlying causes and finding the aetiology helps in proper management of cases...
PREVALENCE OF SENSORINEURAL HEARING LOSS IN CSOM WITH OR WITHOUT CHOLESTEATOMA (STUDY OF 100 CASES)
BACKGROUND Chronic Suppurative Otitis Media is an infectious disease, prevalent in developing countries especially in India and it is the common cause for hearing loss which can be prevented. The objective of the study i...