HEPATIC DYSFUNCTION IN DENGUE FEVER- A PROSPECTIVE STUDY DONE AT A TERTIARY CARE HOSPITAL, SHIMOGA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 1
Abstract
BACKGROUND Dengue is a major health concern, especially in tropical country like India. Hepatic dysfunction in dengue fever is a common feature which complicates the clinical course of the infection and worsen the prognosis. This study was done to assess the frequency and spectrum of liver dysfunction in Dengue infection patients. MATERIALS AND METHODS It was a prospective observational study done in Vaatsalya Hospital, Shimoga, for the duration of 6 months, i.e. from 16/05/2017 to 15/11/2017. All patients attending Vaatsalya Hospital, Shimoga with positive serological tests were included in the study after taking written informed consent. Complete blood count and LFT were done and severity of hepatic dysfunction was based on the extent to which ALT and AST were elevated. RESULTS 100% of patients had elevated AST, 100% patients had elevated AST and 85% patients had elevated ALT. The albumin level was low in 75% patients. Average AST was 316 units/L and average ALT was 156 units/L. CONCLUSION Hepatic involvement in dengue is universal. AST elevation is more common than ALT elevation. Reversal of AST to ALT ratio along with high-grade fever and constitutional symptoms may help in early diagnosis of dengue.
Authors and Affiliations
Malavade Praveen, Girish I
Keywords
Related Articles
- EP ID EP284510
- DOI 10.14260/jemds/2018/13
- Views 106
- Downloads 0
OCULAR MANIFESTATION AND LONG STANDING VISUAL IMPAIRMENT FOLLOWING VENOMOUS SNAKE BITE
[b] OBJECTIVE[/b]: Snake bite is an environmental hazard associated with significant ocular morbidity and some have sight threatening complications. Objective of this study was to determine the ocular manifest...
MANAGEMENT OF HAEMORRHOIDS BY OPEN AND CLOSED HAEMORRHOIDECTOMY– A COMPARATIVE STUDY
BACKGROUND Haemorrhoids are estimated to affect nearly 40% of the population during their lifetime in some form or the other. Milder forms respond to conservative management whereas surgical approach is necessary in the...
ROLE OF ROUTINE SCREENING IMAGING MODALITIES IN THE DIAGNOSIS OF SITUS INVERSUS TOTALIS- OUR EXPERIENCE
BACKGROUND Situs inversus totalis is rare with incidence of one in ten thousand. It is usually associated with dextrocardia (true mirror image) with only 3% - 5% incidence of congenital heart disease, the most common bei...
A STUDY OF BACTERIAL ISOLATES AND THEIR SENSITIVITY PATTERN TO ANTIBIOTICS IN EMPYEMA THORACIS CASES IN A TERTIARY CARE HOSPITAL
BACKGROUND Empyema thoracis refers to accumulation of pus in the pleural space. The pathogenic organisms isolated in cases of empyema depend on prior antibiotic use and route of infection i.e. whether infection arises as...
LARGE GROUP VERSUS SMALL GROUP- A TEACHING PRINCIPLE IN MEDICAL EDUCATION
BACKGROUND Medical education is an evolving scientific field with new modifications and changes in teaching style added continuously for the betterment of medical students. Small group teaching is a new trend compared to...