Hepatoprotective activity of aqueous extract of Cynodon dactylon on paracetamol induced hepatotoxic albino rats
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 1
Abstract
Abstract: Cynodon dactylon is commonly known as Bermuda grass. It is a perennial grass and found all over the India. The plant is a rich source of metabolites such as proteins, carbohydrates, minerals, β-sitosterols, flavonoids, alkaloids, glycosides, terpenoids. The plant has also been used traditionally to treat various ailments like cough, convulsion, anasarca, diarrhoea, dysentery, headache, haemorrhage, hypertension, warts and wounds. The hepatoprotective activity of aqueous extract of Cynodon dactylon at 200mg/kg body weight and 400mg/kg body weight was carried out against paracetamol induced liver damaged in albino rats. Treatment of the animals with extract caused a significant reduction in the values of SGOT, SGPT, and ALP nearly similar to standard N-acetylcysteine. The hepatoprotective activity was further confirmed by histopathological examination of liver specimens of control and treated groups. Keywords: Cynodon dactylon, hepatoprotective, paracetamol, N-acetylcysteine
Authors and Affiliations
Heikham Chandani Devi, Rakesh Singh Moirangthem, Singh Shailendra Vikram, Kh. Sucheta Devi, S. Rita
Keywords
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