HEPATOPROTECTIVE ACTIVITY OF FERONIA ELEPHANTUM FRUIT EXTRACT AGAINST PARACETAMOL INDUCED HEPATIC DAMAGE IN WISTAR RATS
Journal Title: International Journal of Pharmaceutical Applications - Year 2010, Vol 1, Issue 1
Abstract
The objective of the present investigation is to elucidate hepatoprotective activity of Methanolic Fruit extract of Feronia elephantum in paracetamol induced liver damage in Wistar rats. Liver damage was produced by paracetamol (2gm/kg,p.o.) in 1% CMC. The Plant extract (200mg/kg, p.o.) was administered every 24 hrs for seven days, while standard group received N-acetyl l-cystine. At the end of the study the marker enzymes in serum were analysed.The methanolic extract showed significant hepatoprotective activity and efficacy of extract was almost comparable to that of N-acetyl l-cystine.
Authors and Affiliations
Vishnu A. Kangralkar , Shivraj D. Patil , R. M. Bandivadekar , V. S Nandagaon , S. C. Burli
Keywords
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- EP ID EP108744
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