HEPATOPROTECTIVE ACTIVITY OF METHA OLIC EXTRACT OF MADHUCA INDICA ON CARBON TETRA CHLORIDE INDUCED HEPATOTOXICITY IN RATS
Journal Title: Pharmacologyonline - Year 2011, Vol 1, Issue 1
Abstract
The methanol extracts of M.indica studied for hepatoprotective activity against albino rats with liver damage induced by carbon tetrachloride (CCl4). It was found that the methanol extract of M.indica at a dose of 300 mg/kg body weight exhibited moderate protective effect by lowering the serum levels of Glutamate Pyruvate Transaminase (SGPT), Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum bilirubin and Serum alkaline phosphate (SALP) to a significant extent. Present finding demonstrated the methanolic bark extract of Madhuca indica could afford significant dose-dependent protection against CCl4 induced hepatocellular injury.
Authors and Affiliations
Anu Choudhary, A Pandurangan, Anil Bhandari
Keywords
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- EP ID EP151394
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HEPATOPROTECTIVE ACTIVITY OF METHA OLIC EXTRACT OF MADHUCA INDICA ON CARBON TETRA CHLORIDE INDUCED HEPATOTOXICITY IN RATS
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