HEPATOPROTECTIVE ACTIVITY OF TRACHYSPERMUM AMMI (L.), TRIGONELLA FOENUM - GRAECUM L. AND PIPER NIGRUM L. ON HEPG2 CELL LINE
Journal Title: GJRA-Global Journal For Research Analysis - Year 2019, Vol 8, Issue 1
Abstract
The plant seed extract samples were evaluated for its In vitro hepato-protective activity against Ibuprofen induced toxicity in human HepG2 cell line, Firstly the plant seed extract samples were estimated for cytotoxicity with different concentrations from 1000μg/ml to 31.2μg/ml, which resulted to be moderate toxicity to hepatic cell line, and hence the non-toxic concentrations were taken for further studies. The percentage viability of cell line and the cytotoxicity activity of TA, TFG and PN against HEPG2 Cell line was carried out by using MTT assay method. In hepatoprotective study the test substances TA and TFG showed significant percentage protection against Ibuprofen induced toxicity than test substances PN.
Authors and Affiliations
L. Jagapriya
Keywords
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