High-intensity, but not moderate-intensity, exercise increases post-exercise rate of fat oxidation in type 2 diabetics
Journal Title: Journal of Clinical and Translational Research - Year 2016, Vol 2, Issue 2
Abstract
Background: Aerobic exercise is recommended for glycemic and weight control in type 2 diabetes (T2D), but exercise intensity that increase post-exercise fat oxidation has not been established yet. It is expected that high-intensity exercise induce higher absolute oxidations and rates of oxidation of CHO (during) and fat (after) in normoglycemic, but in hyperglycemic it is unclear. Aim: To compare the effects of exercise intensity on CHO and fat oxidation during and after exercise in individuals with T2D. Methods: Eleven persons with T2D, randomly underwent three experimental sessions 72 hours apart: 1) 20 minute of high-intensity exercise (120% of lactate threshold (LT) – 120%LT), 2) 20 minute of moderate-intensity exercise (80% of LT – 80%LT), and 3) 20 minute of control session (CON) – no exercise was performed and the individuals remained seated during the whole time. Percentages of CHO and fat contribution and CHO and fat oxidation rate (mg/min) were analyzed during and after sessions. Results: The rate of CHO oxidation during exercise was significantly higher during 120%LT in relation to 80%LT and CON (18.2 ± 5.6 vs. 9.5 ± 2.7 vs. 1.1 ± 0.4 mg∙min−1), the absolute rate of fat oxidation was significantly higher in 120%LT compared to 80%LT and CON during exercise (13.5 ± 3.3, 9.5 ± 2.2, and 0.7 ± 0.2 mg∙min−1 , respectively, p < 0.05). During the post-exercise oxygen consumption recovery period, only the 120%LT had higher fat oxidation (94.5% vs. 68.1%, p < 0.05), when compared to CON. Both exercise sessions equally elicited a lowered glycaemia during the post-exercise period, but CHO oxidation was lower after 120%LT than CON (0.1 ± 0.2 vs. 0.9 ± 0.5 mg∙min−1 , p < 0.05). Conclusions: Higher intensity elicited an elevated CHO oxidation rate during exercise and a higher percentage of fat utilization during the post-exercise recovery period compared to moderate-intensity exercise and control sessions. Relevance for patients: High-intensity aerobic exercise, even of short duration, may benefit individuals with T2D on the substrate oxidation related to the body fat. Exercise can be an important tool for the prevention and management of T2D due to its effects on carbohydrate and fat metabolism, reduction of body fat, and control of blood glucose.
Authors and Affiliations
Ricardo Yukio Asano, Marcelo Magalhães Sales, Rodrigo Alberto Vieira Browne, José Fernando Vila Nova de Moraes5, Rafael da Costa Sotero6, Gisela Arsa, Jonato Prestes, Johanna Lopez, John Eugene Lewis, Herbert Gustavo Simões
Keywords
Related Articles
- EP ID EP678798
- DOI -
- Views 160
- Downloads 0
Neonatal circumcision and prematurity are associated with sudden infant death syndrome (SIDS)
Background: Sudden infant death syndrome (SIDS) is the most common cause of postneonatal unexplained infant death. The allostatic load hypothesis posits that SIDS is the result of cumulative perinatal painful, stressful,...
Importance of intellectual property generated by biomedical research at universities and academic hospitals
Biomedical research has many different facets. Researchers and clinicians study disease biology and biochemistry to discover novel therapeutic targets, unravel biochemical pathways and identify biomarkers to improve diag...
Effects of prior exercise on glycemic responses following carbohydrate inges on in individuals with type 2 diabetes
Background: Exercise is effective in reducing glycemia, especially when it is performed in the postprandial period. However, no consensus exists in the literature about the effect of exercise on postprandial glucose cont...
Relationship between the Romberg test and the Wii Fit basic balance test and cognition in athletes with concussion
Background: Approximately 30% of individuals with a sport-related concussion present with postural instability. Multiple clinical balance tests exist to diagnose postural instability; yet little is known about the potent...
A double-blind, randomized trial on the effect of a broad-spectrum dietary supplement on key biomarkers of cellular aging including inflammation, oxidative stress, and DNA damage in healthy adults
Background and Aim: Nutritional approaches that ameliorate cellular senescence may have the potential to counteract the effects of chronic disease. This study will investigate the effect of the Healthycell dietary supple...