HIGH SENSITIVE C - REACTIVE PROTEIN AND ITS ASSOCIATION WITH BLOOD PRESSURE – A HOSPITAL BASED STUDY
Journal Title: International Journal of Basic and Applied Physiology - Year 2014, Vol 3, Issue 1
Abstract
Background and Objectives: Although some traditional risk factors such as drinking alcohol, being overweight, a diet high in salt and genetic factors are confirmed risk factors of hypertension, its etiology and pathogenesis are not fully understood. Therefore this study was conducted to find out if there is any association of hsCRP (a marker of inflammation) with blood pressure. Materials and Method: This hospital based case control study included a total of 209 subjects (108 = cases, 101 = control) aged 30 years and above. The hsCRP test was performed by using BioCheck high sensitivity C-reactive protein enzyme immunoassay test kit. Statistical analyses included Independent-Samples T Test, Chi-square test and Spearman’s correlation coefficients. Result: hsCRP was significantly correlated with both systolic blood pressure and diastolic blood pressure (p<0.005). Conclusion: Increased hsCRP was significantly associated with hypertension suggesting a role of inflammation in the development of hypertension and thus estimation of serum hsCRP can be used as a risk assessment tool for prediction of hypertension
Authors and Affiliations
Chandrika Gogoi, Wasima Jahan, Ratan K. Kotokey
Keywords
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