Highly efficient synthesis of tetrahydrobenzo[b]pyrans under visible light promoted by cesium carbonate
Journal Title: Iranian Chemical Communication - Year 2017, Vol 5, Issue 2
Abstract
Multi-component coupling reaction (MCR) is a powerful synthetic tool for the synthesis of biologically active compounds. Development of such multi-component coupling reaction strategies in visible light has been of considerable interest, as they provide simple and rapid access to a large number of organic molecules through a sustainable path. An efficient and green protocol for the synthesis of tetrahydrobenzo[b]pyrans derivatives by one-pot, three component coupling reaction of aromatic aldehyde, malononitrile, and dimedone has been developed using readily available cesium carbonate as the catalyst under visible light. This efficient procedure has the advantages of giving the target compounds in high yields, short reaction times, simple work-up procedure, use of chief and easily available catalyst, and environmentally benign conditions.
Authors and Affiliations
Vinod T. Kamble, Munazza Sadaf, Bushra Saleh Samer
Keywords
Related Articles
- EP ID EP259814
- DOI -
- Views 127
- Downloads 0
Guanidine hydrochloride: An efficient catalyst for the synthesis of 2-hydrazolyl-4-thiazolidinone derivatives under solvent free conditions
A Highly efficient protocol has been developed for the synthesis of 2-hydrazolyl-4-thiazolidinone derivatives installing a one pot three component coupling reaction of an aromatic aldehyde, thiosemicarbazide and maleic a...
Computational determination of character table and symmetry of fullerenes cage as C24 and C28
Fullerene chemistry is nowadays a well-established field of both theoretical and experimental investigations. This study considers the symmetry of small fullerenes cage C24 and C28. Using PM3 program for C24 and C28 f...
The preparation of quinoxaline and 2,3-dihydropyrazine derivatives using Selectfluor as an efficient and reusable catalyst
Selectfluor [1-(chloro methyl) -4-flouro -1,4-di azonia bicyclo[2,2,2] octane bis (tetraflouro-borate)] catalyzed the preparation of quinoxaline and 2,3-dihydo pyrazine derivatives through one -pot condensation of 1,2-di...
Efficient classical synthesis of aminoazines under microwave irradiation
In the present study, Aminoazines were prepared from the reaction of amidrazone hydroiodide with various aromatic aldehydes in the presence of a solid base under microwave irradiation with power level of 850 W for 2-7 mi...
Synthesis of some network polymers with siloxane units as a drug delivery system
New biodegradable network polymers containing siloxane-linked polymeric prodrugs of 5-ammino-2-hydroxybenzoic acid (5-ASA) in the main chain were prepared by ter polymerization of methacrylic acid (MA), 2-hydroxyethylmet...