Histopathological analysis of PediatricBrain Tumors in correlation with Ki-67 labelling index
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
The Central Nervous System tumors arethe second most commontumors occurring in children following Acute lymphoblastic leukemia. These areless frequently analysed due to relatively low incidence of occurrence of these tumors compared to cancers of other organs like aero-digestive tract, cervix and breast. The objective of this study was to correlate the histological grade and Ki 67 expression in various CNS neoplasms and provide a benchmark for future studies assessing data in continuum. This was a retrospective study carried out in our institution on 13 CNS neoplasms arising in children from a total of 100 cases . There was positive correlation between the Ki-67 expression and histological grade showing a proportionate rise in the labelling index with the corresponding histological grade.
Authors and Affiliations
Dr. Martina . V, Dr. S. Jenita Christiana Ranjana
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