Histopathological analysis of PediatricBrain Tumors in correlation with Ki-67 labelling index
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
The Central Nervous System tumors arethe second most commontumors occurring in children following Acute lymphoblastic leukemia. These areless frequently analysed due to relatively low incidence of occurrence of these tumors compared to cancers of other organs like aero-digestive tract, cervix and breast. The objective of this study was to correlate the histological grade and Ki 67 expression in various CNS neoplasms and provide a benchmark for future studies assessing data in continuum. This was a retrospective study carried out in our institution on 13 CNS neoplasms arising in children from a total of 100 cases . There was positive correlation between the Ki-67 expression and histological grade showing a proportionate rise in the labelling index with the corresponding histological grade.
Authors and Affiliations
Dr. Martina . V, Dr. S. Jenita Christiana Ranjana
Keywords
Related Articles
- EP ID EP452681
- DOI 10.9790/0853-1801190105.
- Views 48
- Downloads 0
Pleural Fluid Pseudocholinesterase and Its Ratio to Serum Pseudocholinesterase: For Differentiating Pleural Transudates from Exudates
Context: The lights criteria is the system that has stood the test of time in classifying pleural effusions into transudates and exudates. But studies have shown that there is significant number of misclassification with...
To Evaluate Comparitive Values Ofapplanation, Indentation& Non-Contact Tonometry on Different Refractiveerror Groups
AIM: To compare and contrast the objective measurement of IOP using the Schiotz indentation tonometer, Applanation tonometer and the non-contact air puff tonometer in patients with various refractive errors.MATERIAL& MET...
Role of topical Mitomycin c in the treatment of placoid variant of Ocular surface squamous neoplasia.-A Case report
Ocular surface squamous neoplasia encompasses a varied spectrum of dysplastic, pre invasive and malignant squamous lesions of the conjunctiva and cornea. In this case report a 40 year male patient presented with placoid...
Implants in Glaucoma-An Overview
Glaucoma is a multifactorial optic neuropathy in which there is a characteristic acquired loss of retinal ganglion cell and atrophy of optic nerve. Glaucoma filteration surgery (GFS) has been shown to be more effective a...
“Children with Type 1 Diabetes Mellitus Presenting With Ketoacidosis: Frequency, Severity And Clinical Profile”
Background: Worldwide, approximately 65,000 children aged under 15 years develop T1DM each year. Objective: To identify & describe the frequency and severity of DKA & clinical profile at diagnosis of type 1 diabetes mell...