HISTOPATHOLOGICAL LESION OF GALL BLADDER MUCOSA ASSOCIATED WITH CHOLELITHIASIS
Journal Title: JOURNAL OF ANATOMICAL SCIENCES - Year 2017, Vol 25, Issue 2
Abstract
Aims & Objectives: To study the various changes in gall bladder mucosa in those gall bladder specimens who possesses gall stones and compare and correlate the data with the similar studies done in the past in different part of India. Material & Methods: It is a hospital based study done in Santosh Medical College and Hospital, Ghaziabad. The duration of this study was 2 years. Total 131 open cholecystectomy specimens with complete gallstones were examined. We included male and female patients of all the age group. Patient of cholelithiasis diagnosed by radiology and recommended for cholecystectomy formed the study population. Autolysed cholecystectomy specimens and cholecystectomy specimens without gallstone were excluded from this study. Results: We found that maximum number of specimens had chronic cholecystitis 97.7 %, followed by Rokitansky-Aschoff sinuses 22.9%, muscular hyperplasia 15.3%, epithelial hyperplasia 8.4%, fibrosis and ulceration 3.8%, carcinoma 3.1%, antral metaplasia 2.3%, xanthogranulomatous cholecystitis 2.3%, eosinophilic cholecystitis and intestinal metaplasia each presented with 0.8%. In our study, carcinoma was always present with pigment type stone. Conclusion: Carcinoma of gallbladder was found in (3.10%) cases which is higher ever reported in India. With the advancement of investigational procedures, more cases related to gallbladder pathologies have come to light, thus making it very much relevant to pursue a research in this field. Moreover, this study will bring forth to light the knowledge which will be advantageous to the population, dieticians as well as medical practitioners.
Authors and Affiliations
Arvind Yadav
Keywords
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