HISTOPATHOLOGICAL PROFILE OF PROSTATECTOMY SPECIMENS IN A TERTIARY HOSPITAL
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 13
Abstract
BACKGROUND Diseases of the prostate are common causes of morbidity and mortality in adult males. Benign prostatic hyperplasia is an extremely common disorder in men over the age of 50. Other frequently encountered diseases affecting the prostate are prostatitis, benign prostatic hyperplasia and prostatic cancer. Histopathological examination of prostate biopsy specimen is required to rule out the benign or malignant enlargement of prostate gland in older men. We wanted to study the histopathological patterns of prostatic diseases in prostatectomy specimens in RIMS Hospital. METHODS A 5-year cross sectional study was carried out between October 2007 and October 2012 in the Department of Pathology, RIMS. All the prostate specimens received for histopathological examination during the period of study were fixed, processed, and stained with Haematoxylin and Eosin, and examined for various prostatic lesions. RESULTS A total of 73 specimens were studied out of which 53 (72.60%) were Benign Prostatic Hyperplasia (BPH), making it the commonest lesion. 11 (15.07%) were BPH with nonspecific prostatitis while 2 (2.74%) were BPH with granulomatous prostatitis. BPH with Prostate Intraepithelial Neoplasia (PIN) was seen in 4 (5.48%) specimens. Only 3 (4.11%) were malignant. All the malignancies were Adenocarcinomas. The mean age of BPH cases was 69.2 years ranging from 54 to 80 years. The malignancies were seen in the seventh and the eight decades. CONCLUSION BPH accounted for about three-fourths (72.60%) of the prostatic tissue samples. Few pre-malignant (PIN) and malignant lesions were found. Other lesions like nonspecific prostatitis, granulomatous prostatitis were also encountered.
Authors and Affiliations
Phuritshabam Pinky, Vaskerjeet Konsam, Alpana Laisom, Athokpam Marina, Ronal Singh Rajkumar, Leishangthem Nabina, Rajesh Singh Laishram
Keywords
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- EP ID EP615885
- DOI 10.18410/jebmh/2019/224
- Views 85
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