Histopathological spectrum of papillary carcinoma thyroid – a 4 year retrospective analysis
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2018, Vol 4, Issue 2
Abstract
Introduction: Papillary carcinoma of thyroid is the most common malignant tumor constituting about 80% of all malignancies of thyroid. It has an indolent course with an excellent prognosis and numerous histological variants have been reported till date. Also various associated lesions are also being noted, of which hashimotos thyroiditis is one of the common lesions. Objective:1)To analyse various histopathological features of papillary carcinoma thyroid. 2) To evaluate the presence or absence of hashimotos thyroiditis in the background of papillary carcinoma. Design: Hospital based cross sectional study. Subject: Histopathologically diagnosed cases of papillary carcinoma thyroid in a 4 year period. Methods: Retrospective analysis of histopathologically diagnosed cases of papillary carcinoma thyroid has been done. Results: Papillary carcinoma thyroid is more prevalent among females with most of the lesions showing conventional papillary pattern in 72.8% cases. Almost all the cases have the typical nuclear features described. Hashimotos thyroiditis is seen in 44.2% of the cases. Papillary micocarcinoma seen in 17.1% patients. Multifocality is seen in 28.5%. The association between papillary carcinoma and hashimotos thyroiditis was evaluated using chi square test, p value= 0.001 and was found to be statistically significant. Conclusion: Our study has well correlated with the literature, with regards to epidemiological profile and the predominant histopathological pattern. Hashimotos thyroiditis is the predominant associated lesion.
Authors and Affiliations
Anupama Raj K, Benzy Paul
Keywords
Related Articles
- EP ID EP337948
- DOI 10.17511/jopm.2018.i2.18
- Views 125
- Downloads 0
Comparison of Z. N. staining & fluorescent microscopy in detection of M. Tuberculosis bacilli in Fine needle aspiration smears
Aims: To compare ZN stain method with Fluorescent method for detection of tuberculous bacilli in FNA smears in terms of sensitivity & feasibility. Settings and Design: A Prospective study was conducted in the department...
A clinicopathological study of salivary gland tumors
Background:To evaluate tumors involving major and minor salivary glands, histopathology is an essential diagnostic method and is the gold standard. This study was carried out to know the incidence of salivary gland tumor...
Mycosis fungoides- adnexotropic variant -a rare case report
Mycosis fungoides accounts for <1% of non hodgkins lymphomas. It is the commonest cutaneous T cell lymphoma comprising 44% of cutaneous lymphomas. It is clinically characterised by patch, plaque and tumor nodules. Herein...
Intraorbital, extraconal cavernous hemangioma: a common tumor at an uncommon site-a case report
A wide variety of processes can produce space occupying lesions in and around the orbit including benign neoplasms, malignant neoplasms, vascular lesions, inflammatory diseases, congenital lesions etc. Cavernous hemangio...
Inflammatory PAP smears and its microbiological association: A prospective study
The infections of the genital tract are common in reproductive-age women. The Papanicolaou (Pap) test is a simple, quick, and painless cytology procedure, based on picking up of cells from the uterine cervix and used as...