Histopathological variations in endometrial biopsies
Journal Title: International Journal of Medical and Health Research - Year 2019, Vol 5, Issue 1
Abstract
Objective: 1) To evaluate endometrial variations in women with abnormal uterine bleeding. 2) To study spectrum of patterns of endometrium in different age groups. Materials and Methods: A retrospective study was undertaken to review the histopathological reports of all endometrial biopsies over a period of 4 years i.e. July 2010 to July 2014 in department of pathology of Veer Chandra Garhwali institute of medical sciences, Srikot, Srinagar, Garhwal, Uttarakhand. Data was entered in Microsoft excel and managed in statistical package for the social sciences (SPSS) version 16. Analysis was done in the form of percentages and represented as tables where necessary. Results: A total of 200 patients were evaluated during the study period. The histopathological findings were categorized into functional and organic causes 150 (75%) cases revealed only functional pathology and a smaller group of cases 50 (25%)) showed definitive endometrial pathology. Maximum number of cases were observed in age group of 31-40 years with proliferative phase (60 cases, 40%) being the most common functional lesion and chronic endometritis (10 cases, 30.32%) the most common organic lesion, 3 cases (3.14%) of endometrial carcinoma were observed. Other endometrial patterns were secretory phase 20(12.57%), proliferative phase 62(38.99%), disordered proliferative endometrium 1(0.62%), 1 (0.62%), irregular shedding 1 (0.62%), chronic endometritis 3 (1.88%), pregnancy related 1 (0.62%), atrophic endometrium 6 (3.77%). Conclusion: Endometrial biopsy is a safe, efficient and cost-effective means of evaluating the uterine endometrium. The functional endometrial changes account for the highest morphological patterns while malignant lesions account for the least common pattern of the endometrial biopsies evaluated for various gynaecological problems such as menstrual irregularities, dysfunctional uterine bleeding, infertility etc.
Authors and Affiliations
Dr. Neha Batra, Dr. Sheela Chaudhari, Dr. Deepa Hatwal
Keywords
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