Histopathological Vs. cytological findings in cervical lesions (Bethesda System 2001) A comparative study
Journal Title: International Journal of Biomedical and Advance Research - Year 2016, Vol 7, Issue 11
Abstract
Background: Cervical malignancy is the major health burden in India. For detection in early stage, the screening test is PAP smear. To check the sensitivity and specificity of Bethesda system, the cytological findings have to be correlated with histology considering histopathology as gold standard. Objective: To study usefulness of cytology in detecting various cervical lesions, to evaluate and interpret the cases of epithelial lesions and correlation of cytological findings with subsequent follow-up histology sections. Materials and Methods: A retrospective review of PAP smears in Dhiraj General Hospital in the period from May 2015 to September 2016. They were correlated with corresponding follow-up biopsies using revised 2001 Bethesda System. Analysis of different factors causing discrepancies was done. Results: The PAP smear has overall sensitivity of 86.04%, specificity 42.85%, positive predictive value 90.24 %, negative predictive value 33.33 % and accuracy 80% in detecting low/high grade lesions and malignancy.
Authors and Affiliations
Dr. Kuntal Devesh Patel, Nisarg Champaneria, Shreya Shah, Mihir Sharma, Jasmin H Jasani, Rippal Bhimani
An innovative method for retrograde tracheal intubation using prolene suture and enteric feeding catheter
Retrograde intubation is a well established technique for intubating a patient with difficult airway. Since the first description of retrograde intubation in 1960 several modifications have been reported. However, all te...
Thoracic vertebral synostosis & its clinical importance
Background: Thoracic vertebral synostosis is of interest not only to the anatomist but also to surgeons, neurologist, orthopedician, radiologist, anaesthetics and for forensic medicine also. Various vertebral anomalies h...
Study of visual morbidity among the school going children in rural part of Central India
Background: Visual morbidity is an important factor affecting the learning ability, personality and confidence of growing children. Early detection and treatment of visual morbidity is an easy way to improve child health...
Significance of liver enzymes as a baseline investigation in recently diagnosed HIV positive patients
Background: Liver disease is a common feature in patients with Human Immunodeficiency Virus (HIV) infection and hence it is important to consider its involvement when treating HIV infected patients. In this study we anal...
Analysis of Laboratory Critical value Reporting Pattern at clinical biochemistry laboratory of Tertiary health care Center
Objectives: Objective of the study is to analyze critical value reporting data to find frequency of critical reporting, distribution of critical values across reportable range and across hospital segments and reasons for...