HIV-1 INFECTION AND ITS INFLUENCE ON LIPID METABOLISM AND CARDIOVASCULAR DISEASE
Journal Title: INTERNATIONAL JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH - Year 2016, Vol 4, Issue 4
Abstract
It is important to recognize the fact that human immunodeficiency virus (HIV-1) infection by itself can have its effect on lipid metabolism irrespective of initiation of highly active antiretroviral therapy (HAART). For example, it has long been recognized that triglyceride level increases markedly with HIV-1 disease progression, likely reflecting persistence of an inflammatory state as well as wasting. A previous research has showed an increase in mean triglyceride value from 91 mg/dL in HIV-1 negative individuals to 166 mg/dL among HIV-1 infected group and 231 mg/dL in people living with AIDS.
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