HIV status in lymphadenopathy: A study of 200 cases
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 5
Abstract
Introduction- Generalized lymphadenopathy was one of the characteristic manifestations of AIDS epidemic, even before its etiology was recognized.1 Cervical, axillary and inguinal lymph nodes are usually involved.2 Tuberculous cervical lymphadenitis is being increasingly recognized and diagnosed with an increase in HIV infection.3 FNAC is an important diagnostic tool in the evaluation of lymphadenopathy in HIV. (4)Most opportunistic infections and malignancies can be correctly diagnosed, with immediate institution of treatment.5 Histopathological examination of lymph node biopsies is the gold standard of diagnosis and is helpful in differentiating between reactive and malignant conditions, which closely resemble each other.6 Material and Methods: 200 patients with lymphadenopathy were tested for HIV status, and subjected to either fine needle aspiration or biopsy of the lymph nodes. Epidemiological data, as well as the results of biochemical, cytological and histopathological findings were then compiled. Results: The number of HIV positive cases was found out to be 9 (4.5%). All the nine patients were HIV-1 positive. Among the HIV positive cases, males were 7 and females were 2 and 7/9 had cervical lymphadenopathy. The final diagnosis was tuberculosis in 4 cases (44.5%), suppurative lymphadenitis in 3 (33.3%) and reactive hyperplasia in 2 cases (22.2%). Conclusion: We studied the epidemiological data, HIV status, cytopathological and histopathological findings in 200 patients with lymph node enlargement. While in patients who were HIV negative, the most common cause of lymphadenitis was reactive hyperplasia, in HIV positive patients, it was tuberculosis. This is because it is a very common opportunistic infection in AIDS, and endemic in our area.
Authors and Affiliations
Anil Kumar Suri, Dimpi Ohri, Puneet Kaur, Ankur Suri
Keywords
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