Study of hematological changes in chronic renal failure
Journal Title: MedPulse -International Medical Journal - Year 2018, Vol 5, Issue 7
Abstract
Background: Chronic renal failure is defined as kidney damage, glomerular filtration rate GFR) < 60 ml/min/1.73 sq.m for a period of ≥ 3 months. Kidney diseases rank third amongst life threatening disease. Anemia is a common sequelae of chronic kidney disease associated with significant morbidity and mortality. Most of the patient of chronic renal failure present with severe anaemia, bleeding tendancies which exacerbates with underlying illness. Aims and objectives: 1 To study hematological manifestations, demographic feature and clinico-hematological correlation of chronic kidney disease. Materials and Method: This study was a cross sectional prospective observational study. Inclusion Criteria: Patient with chronic kidney disease with age more than 12years Exclusion criteria:1.Patient with other systemic illness with chronic kidney disease 2.Pregnancy 3.Aplastic anaemia 4.Known hematological malignancy and myelodysplasia with chronic kidney disease 4.Patient with chronic kidney disease with uremic encephalopathy with vitally unstable. Results: Total 110 patients were studied among patients 30 (27.27 %) were in age groups >60 yrs, there were 68 male and 42 females, mean Hb of precent was 7.047+ 1.84 gm, 71.81 %(79) of patients were normocytic normochromic anaemia, mean of total platelets were 2.04+ 0.94 lakhs and mean TLC were 5764+2.11.Conclusions: In present study majority patients were in age groups >60 yr, male predomint, all patients had anemia, as stage advances severity of anaemia increases. mejority patients had normocytic and normochromic anaemia. Mean MCV, MCH, MCHC were in normal ranges in cronic kidney disease. As stage progresses TLC count remains on higher side and platelet count were decreases.
Authors and Affiliations
D P Bhurke, Subodh V P, Mohammed Ubaidulla Mohammed Ataulla
Keywords
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- EP ID EP487822
- DOI 10.26611/100571
- Views 85
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