HIV/AIDS ASSOCIATED ISOSPORA BELLI INFECTION IN KUMAUN REGION, UTTARAKHAND
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 52
Abstract
BACKGROUND Human immunodeficiency virus (HIV) seropositive patients usually suffer from opportunistic intestinal parasitic infections leading to high mortality and morbidity. Knowledge about the aetiological agents in HIV can often guide the treatment. The objective of this study was to determine the prevalence of Isospora belli infections in HIV-positive patients with diarrhoea attending Dr. Susheela Tiwari Government Hospital, Haldwani and its correlation with CD4 + T lymphocytes counts. MATERIALS AND METHODS All the HIV-positive patients of both the sexes and all age groups presenting with diarrhoea to ART Centre, Dr. Susheela Tiwari Government Hospital, Haldwani were included in the study. A total of 104 patients were enrolled during the study period by consecutive sampling method. The samples were processed using saline, iodine mount and modified Ziehl-Neelsen staining technique to identify the presence of Isospora belli oocysts. RESULTS The prevalence of Isospora belli infection in the study was 16.3%. It was observed to be higher among patients with CD4+ T cell counts ≤200 cells/µL in patients with chronic diarrhoea and in patients not taking Anti-retroviral therapy. CONCLUSION It is recommended that stool samples of HIV seropositive patients should be examined routinely for opportunistic intestinal parasites like Isospora belli in order to institute appropriate treatment.
Authors and Affiliations
Archana Mohan, Umesh Umesh, Mukesh Kumar, Ashok Kumar
Keywords
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- EP ID EP220220
- DOI 10.14260/Jemds/2017/857
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