HLA – B association in psoriasis
Journal Title: International Journal of Medical Research and Review - Year 2016, Vol 4, Issue 5
Abstract
Background: Psoriasis is a common skin disorder with prevalence varying from 0% to 11.8% in different population. HLA association with psoriasis is well established with very little information about Indian Population. Aim: To determine the HLA-B pattern and its association in psoriasis patients. Materials and Methods: Fifty cases and 50 controls were enrolled in the study. HLA-B typing was done by PCR-SSP method and the results was analyzed and interpreted. Results: The alleles that were found in higher frequency in the cases than in the controls were – HLA-B*35 (34%), HLA-B*15 (26%), HLA-B*40 (26%) and HLA-B*18 (14%). Conclusion: HLA-B*18 and HLA-B*40 show a strong association with psoriasis.
Authors and Affiliations
Ashwin Anandan, Krishnamoorthy Radhakrishnan, Ravindra Prasad Thokala, Vinod Kumar Panicker, Murugan Sundaram
Keywords
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