Homocysteine: Association with Preeclampsia and its Severity and Correlation with Maternal and Fetal Outcome of Preeclamptic Women
Journal Title: PARIPEX-Indian Journal of Research - Year 2016, Vol 5, Issue 8
Abstract
OBJECTIVES: To study the homocysteine levels among normal, mild and severe preeclamptic pregnant women, its association with severity of preeclampsia, and Maternal and fetal outcome in pregnancy for any association with homocysteine levels. METHODS: 120 pregnant women were tested for serum homocysteine levels and were followed until delivery for acute kidney injury, pulmonary edema, DIC, abruptio placenta. Similarly, birth weight, intrauterine growth restriction, intrauterine death, neonatal mortality was recorded. RESULTS: In our study, mean homocysteine levels in : normal pregnancy:6.65 micromole/l, mild preeclampsia: 11.58+/-2.38 micromole/l,severe preeclampsia: 16.67+/-10.1 micromole/l. Maternal homocysteine levels more than 15micromole/l was associated with maternal and neonatal morbidities. CONCLUSION: Preeclampsia is associated with hyperhomocysteinemia. Homocysteine levels are directly related to severity of preeclampsia. Elevated maternal homocysteine levels is associated with maternal and neonatal morbidities.
Authors and Affiliations
DR. S. ANURADHA, DR. RIZWANA TAJ. T.
Keywords
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