How we can modify risk of breast cancer?
Journal Title: Przegląd Menopauzalny - Year 2005, Vol 22, Issue 6
Abstract
The multi-step process of carcinogenesis can be delayed, arrested or reversed by natural or synthetic agents. There are several independent risk factors for breast cancer development. Estimation of a women’s risk for breast cancer development is essential to identifying women who are most likely to benefit from chemoprevention. Treatment options for women who were at risk include increased surveillance, chemoprevention and prophylactic mastectomy. In the National Surgical Adjuvant Breast and Bowel Project (NSABP) PI tamoxifen treatment 20 mg/day resulted in a 49% and 50% reduction of invasive and non-invasive breast cancer. Raloxifene is being evaluated in comparison with tamoxifen in the STAR study. The main outcome measure is breast cancer incidence and the results are expected in 2006.
Authors and Affiliations
Monika Zbucka, Monika Leśniewska, Paweł Knapp, Sławomir Wołczyński
Keywords
Related Articles
- EP ID EP83620
- DOI -
- Views 80
- Downloads 0
Wpływ HTZ na choroby układu sercowo-naczyniowego – przegląd piśmiennictwa
W artykule autorzy omawiają wpływ HTZ (hormonalnej terapii zastępczej) i ETZ (estrogenowej terapii zastępczej) na częstość występowania chorób układu sercowo-naczyniowego. Brak zgodności pomiędzy wnioskami wynikającymi z...
Local estrogens administration
Updated data on topical oestrogen treatment are presented. Basic molecular mechanisms (receptor and extrareceptor activities) of oestrogens action, particularly in local (urogyneacological) treatment are described. Cur...
The Moschcowitz operation as a therapeutic method in case of enterocoele
Our objective was to present the case of patient with iatrogenic enterocoele after the Manchester operation performed 3 years ago due to pelvic organ prolapse. The pouch of Douglas was successfully obliterated with the...
The influence of ITT analysis on the evaluation of success rate in the stress urinary incontinence treatment with IVS tape
There are several options to minimize bias during analysis of the results of treatment. It is not possible to organize double blind studies for operative stress urinary incontinence treatment. Aim of the study: The aim...
Prognostic significance of sVEGFR-1 in indentification of resistance to cisplatin and paclitaxel chemotherapy in ovarian cancer patients
Objectives: Most of the patients (>80%) with ovarian cancer require primary debulking surgery and adjuvant chemotherapy as a standard treatment. Chemotherapy including paclitaxel and cisplatin/carboplatin is mainly used...