http://viralhepatitisjournal.org/archives/archive-detail/article-preview/the-effect-of-switch-treatment-on-liver-fibrosis-a/40275
Journal Title: Viral Hepatitis Journal - Year 2020, Vol 26, Issue 2
Abstract
Objectives: To investigate the seroprevalence of hepatitis A virus (HAV) infection in children with chronic hepatitis B virus (HBV) infection and to immunize patients who did not have anti-HAV immunoglobulin (Ig) G level in protective titer. Materials and Methods: A retrospective analysis was made in 79 children with chronic HBV infection between January 2017 and December 2018. Results: Of the patients with a mean age of 11.5±4.6 years (1-18 years), 64.6% were boys and 35.4% were girls (male/female=51/28). Anti-HAV (Ig) G was positive in 72.2% (n=57) of the cases. According to gender, the rate of sero-positivity was found to be 72.5% (n=37) in boys and 71.4% (n=20) in girls. HAV immunization was determined at the lowest rate (8.1%) in the 14-18 years age group. Although 3 patients vaccinated against HAV were anti HAV-IgG negative, and 39 patients who were not vaccinated were anti-HAV IgG positive. Conclusion: The seroprevalence of HAV should also be evaluated in children with chronic HBV infection. Morbidity and mortality due to HAV infection can be prevented by vaccinating non-immune patients.
Authors and Affiliations
Uğur Deveci, Ufuk Acar
Molecular Characterization of Hepatitis B Virus Strains Isolated from Chronic Hepatitis B Patients in Southeastern Region of Turkey
Objectives: The aim of the present study was to assess the molecular aspects of HBV strains isolated from chronic hepatitis B (CHB) patients, in the Southeastern region of Turkey. Materials and Methods: The study involv...
Viral Hepatitis Prevalence in Two Cognitively Different Risk Groups
Objectives: This study aimed to investigate whether patient awareness of viral hepatitis affected the prevalence of the condition by comparing the awareness levels in two high-risk groups with different cognitive abiliti...
Effect of Advanced Fibrosis Presence on Adherence to Hepatocellular Carcinoma Surveillance in Chronic Hepatitis C Patients with Sustained Virologic Response
Objectives: Although hepatocellular carcinoma (HCC) screening is accepted as standard care in patients with chronic hepatitis C (CHC) diagnosis, sustained viral response (SVR) has been obtained by treatment and it is not...
Intravenous Drug Use Rates and Results of Direct-acting Antiviral Treatment in Prisoner Patients
Objectives: Intravenous drug use (IVDU) is more common in prisoner patients, and this is a global problem. Hepatitis C virus (HCV) infection is higher in prisoners than general population. In our study, we aimed to exami...
Examination of Mutations in the HBsAg and Polymerase Genes Induced by Pegylated Interferon Alpha and Oral Antivirals Used in the Treatment of Chronic Hepatitis B
Objectives: The Hepatitis B Virus is a virus having high mutation frequency due to having a high replication capacity and not having error correction capability in reverse transcription.It is aimed to examine the mutatio...