HYDROGEN SULFIDE SYSTEM ATTENUATES INJURY BY HYPERGLYCEMIA AND STRESS: ROLE OF MESENTERIC ADIPOCYTES IN AGED ANIMALS
Journal Title: Праці Наукового товариства ім. Шевченка - Year 2018, Vol 52, Issue 2
Abstract
The mesentery is one of recently described separate organs which functions and its ability to protect injury are still unclear. Adipocytes are a part of mesentery (MAC), however, it is a little known about their age-related changes, reactive response during damage induced by hyperglycemia, stress, and their interaction. Hydrogen Sulfide (H2S) system is key endogenous cytoprotectvite system that operated by catalytic activities of Cystathionine-γ-lyase (CSE), Cystathionine-β-synthase (CBS), and Sulfite Oxidase (SUOX) but their role in adipocyte cytoprotection are still unknown. To evaluate the CBS, CSE, SUOX activities in the mesenterium and ultrastructural changes of MAC in aged rats fed with HSD, at stress induction, and modification of H2S synthesis by NaHS and hybrid nonsteroid anti-inflammatory drugs H2S-acytylsalicylic acid (H2S-ASA).
Authors and Affiliations
Oleh Revenko, Natalia Zaichko, John Wallace, Oksana Zayachkivska
Keywords
Related Articles
- EP ID EP495621
- DOI 10.25040/ntsh2018.02.115
- Views 107
- Downloads 0
ПОКАЗНИКИ ІНСУЛІНОРЕЗИСТЕНТНОСТІ У ПАЦІЄНТІВ З ІШЕМІЧНОЮ ХВОРОБОЮ СЕРЦЯ БЕЗ ЦУКРОВОГО ДІАБЕТУ ПІД ЧАС ЛІКУВАННЯ СТАТИНАМИ
Актуальність. Серцево-судинна патологія залишається провідною причиною захворю ваності, інвалідизації та смертності населен ня у всьому світі, незважаючи на поліпшення діагностики та результати лікування. Пато ге...
THERMOMECHANICAL PROPERTIES AND ELECTRICAL CONDUCTIVITY OF POLYMER-POLYMER COMPOSITES BASED ON POLYVINYL ALCOHOL AND POLYANILINE
The mechanic-chemical method used to produce polyvinyl alcohol (PVA) and polyaniline (PANI) composites. For synthesis, PVAs with a molecular weight of 40.0.103 and a residual amount of acetate groups of 3.2% were use. Po...
Role of histamine in gastric secretion: From discovery to clinical application (A tribute Leon Popielski to 150-anniversary from his birth)
Professor of Lviv National Medical University (formerly known as Jan Kazimierz Lemberg University), Ukraine, Leon Popielski was the fi rst to recognize that histamine stimulated gastric acid secretion 100 years ago, at 1...
Стаціяльний розподіл прісноводних молюсків у водоймах природоохоронних об’єктів міста Києва [Distribution of freshwater molluscs on stations in water-bodies of protected areas in Kyiv city]
The distributions of freshwater molluscs on stations were monitored over four years (2008-2011) in water-bodies of protected areas in Kyiv City. Sixteen species of freshwater molluscs were recorded in investigated region...
THE TlInS2–ZnS SYSTEM AND THE PROPERTIES OF THE TlInS2:Zn2+ CRYSTAL
Interactions of components in the TlInS2–ZnS systems were investigated by physico-chemical analysis methods. The system is of the eutectic type with limited mutual solid solubility of the starting components: L + ...