Hypokalemic quadriparesis due to renal tubular acidosis in a patient with Sjögren’s syndrome: A case series

Journal Title: Journal of Advances in Internal Medicine - Year 2014, Vol 3, Issue 1

Abstract

We report two cases of female patients presented with hypokalemia secondary to renal tubular acidosis. Sjögren’s syndrome was diagnosed in both the patients on the basis of histopathological and autoantibodies tests. The patients were treated with potassium and bicarbonate supplementation. Renal involvement in Sjögren’s syndrome is not uncommon and may precede sicca complaints. The pathology in most cases is a tubulointerstitial nephritis causing distal renal tubular acidosis and rarely, hypokalemic paralysis. The complications of renal tubular acidosis include life threatening hypokalemia, nephrolithiasis, chronic renal failure, growth retardation and osteomalacia. These consequences can be avoided if the diagnosis is made early and lifelong potassium and alkali supplementation is initiated. Primary Sjögren’s syndrome should be considered in women with acute weakness and hypokalemia.

Authors and Affiliations

Abhishek Maskey*| Department of Nephrology;Nepal Medical College and Teaching Hospital, Kathmandu, Nepal., Neeraj Singh| Department of Nephrology;Nepal Medical College and Teaching Hospital, Kathmandu, Nepal., Santosh Gautam| Department of Internal Medicine;Nepal Medical College and Teaching Hospital, Kathmandu, Nepal., Prashant Bhattarai| Department of Nephrology;Nepal Medical College and Teaching Hospital, Kathmandu, Nepal., Prakash Poudyal| Department of Nephrology;Nepal Medical College and Teaching Hospital, Kathmandu, Nepal., Dhiraj Narayan Manandhar| Department of Nephrology;Nepal Medical College and Teaching Hospital, Kathmandu, Nepal., Pramod Kumar Chhetri| Department of Nephrology;Nepal Medical College and Teaching Hospital, Kathmandu, Nepal.

Keywords

Related Articles

Ulcerative Colitis complicated by lower limbs thromboemboilism- an unusual case scenario

Patients with inflammatory bowel disease (IBD) have an increased risk of vascular complications. In ulcerative colitis, 10% of deaths are attributed to thromboembolic complications. Arterial thromboembolic complications...

EFFICIENCY OF CO-INOCULATION PHOSPHATE SOLUBILIZER MICROORGANISMS (PSM) AND PLANT GROWTH PROMOTING RHIZOBACTERIA (PGPR) ON MICRONUTRIENTS UPTAKE IN CORN (ZEA MAYS L.)

Efficient use of p-solubilizer, plant growth promoting rhizohactoria (PGPR) applied as the biofertilizers is important in corn (Zea mays L.) production to maximize producer’s economic returns and maintain soil and water...

INDUCTION OF DROUGHT TOLERANCE WITH SEED PRIMING IN WHEAT CULTIVARS (TRITICUM AESTIVUM L.)

Delay in planting and low precipitation (<300mm annual) in wheat (Triticum aestivum L.) farming is the major problem in the irrigated and rainfall lands of Iran. A factorial experiment for evaluating the effects of seed...

Serial Ascitic Fluid Analysis – Prognostic Marker for Adverse Outcome in Spontaneous Bacterial Peritonitis in Liver Cirrhosis?

Background and Aims: Cirrhosis is a frequent cause of hospital admissions in Nepal with spontaneous bacterial peritonitis (SBP) being a major determinant of mortality. Limited diagnostic options preclude early risk strat...

Falsely Elevated Acetaminophen Levels in the Setting of Hyperbilirubinemia

A 51-year-old male with a history of heavy alcohol abuse presented with alcoholic hepatitis and acute renal failure. Although he denied acetaminophen (APAP) ingestion, he was found to have elevated APAP levels that persi...

Download PDF file
  • EP ID EP4780
  • DOI http://dx.doi.org/10.3126/jaim.v3i1.10701
  • Views 460
  • Downloads 23

How To Cite

Abhishek Maskey*, Neeraj Singh, Santosh Gautam, Prashant Bhattarai, Prakash Poudyal, Dhiraj Narayan Manandhar, Pramod Kumar Chhetri (2014). Hypokalemic quadriparesis due to renal tubular acidosis in a patient with Sjögren’s syndrome: A case series. Journal of Advances in Internal Medicine, 3(1), 30-33. https://europub.co.uk/articles/-A-4780