Hypolipidemic Activity of Spinacia Oleracea L. in Atherogenic Diet Induced Hyperlipidemic Rats.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2012, Vol 1, Issue 1
Abstract
Spinacia oleracea (spinach) of family Amaranthaceae is an important plant used traditionally for medicinal purposes. Hyperlipidemia was induced by treated orally with atherogenic diet. In atherogenic diet induced hyperlipidemic model, the rats receiving Spinacia oleracea powder showed significant reduction in total cholesterol, triglycerides, total protein and elevation of high density lipoprotein cholesterol. Spinacia oleracea was found to possess significant hypolipidemic activity. The results also suggest that Spinacia oleracea powder at 200mg and 400 mg/kg b.wt. concentrations are an excellent lipid-lowering agent.
Authors and Affiliations
Ranjan Kumar Giri*| Institute of Pharmacy and Technology, Salipur, Cuttack – 754202, India., Sunil Kumar Kanungo| Institute of Pharmacy and Technology, Salipur, Cuttack – 754202, India., Niroj K. Tripathi| Department of Zoology, Berhampur University, Berhampur, Ganjam, Odisha, India.
Keywords
Related Articles
- EP ID EP1503
- DOI -
- Views 618
- Downloads 36
OCCURRENCE OF MALIGNANT TUMORS OF PARANASAL SINUSES IN KARNATAKA
Introduction: malignancy of paranasal sinuses is wide spread. Paranasal sinuses are in close anatomical relationship with skull viscera. Clinical assessment get hampered by surrounding bony structures, diagnostic radiolo...
MOLECULAR CHARACTERIZATION OF THE 16S RRNA GENE OF HELICOBACTER PYLORI ISOLATED FROM STOMACH BIOPSY IN GASTRITIS PATIENTS
Background: Helicobacter pylori is now accepted as the most important cause of gastritis in human. There is a growing body of literature on the detection of H. pylori 16S gene in gastritis patients. The study was aimed...
Antigenotoxic studies of Salvadora persica (Miswak) root extract in mice
The present study was aimed to investigate in-vivo antigenotoxic effect of repeated exposure of hydro-alcoholic extract of Salvadora persica (SP). Two doses of root extract of SP (200 and 400 mg/kg) were administered to...
ASSESSMENT OF HYPERCOAGULABILITY STATE AMONG SUDANESE SICKLE CELL PATIENTS
Sickle cell anaemia is one of the causes of morbidity and mortality in Africa. This study aimed to determine the coagulation profile, including D-Dimer level, Fibrinogen level and TAT, and also to determine haematolgical...
Development and Validation of HPLC Method for the Estimation of Anti-HIV Drug Abacavir Sulphate in Bulk and Pharmaceutical Formulations.
Objective: Analytical method development and validation was useful for estimation of drugs in bulk and biological fluids. They help to improve the reliability, consistency and accuracy of analytical data. Present investi...