Hypolipidemic Activity of Spinacia Oleracea L. in Atherogenic Diet Induced Hyperlipidemic Rats.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2012, Vol 1, Issue 1
Abstract
Spinacia oleracea (spinach) of family Amaranthaceae is an important plant used traditionally for medicinal purposes. Hyperlipidemia was induced by treated orally with atherogenic diet. In atherogenic diet induced hyperlipidemic model, the rats receiving Spinacia oleracea powder showed significant reduction in total cholesterol, triglycerides, total protein and elevation of high density lipoprotein cholesterol. Spinacia oleracea was found to possess significant hypolipidemic activity. The results also suggest that Spinacia oleracea powder at 200mg and 400 mg/kg b.wt. concentrations are an excellent lipid-lowering agent.
Authors and Affiliations
Ranjan Kumar Giri*| Institute of Pharmacy and Technology, Salipur, Cuttack – 754202, India., Sunil Kumar Kanungo| Institute of Pharmacy and Technology, Salipur, Cuttack – 754202, India., Niroj K. Tripathi| Department of Zoology, Berhampur University, Berhampur, Ganjam, Odisha, India.
Keywords
Related Articles
- EP ID EP1503
- DOI -
- Views 614
- Downloads 36
HEMATOPOIETIC GROWTH ASPECTS: MANIFESTATION OF VULNERABILITIES AND PROSPERITY IN HUMAN CANCER
A regular reaction of cancer medicine is bone marrow concealment. The resulting myelosuppression and iron deficiency can cause huge morbidity and mortality for patients. Mediators, for example granulocyte colony stimul...
Study of effect of solubility of a sparingly water soluble drug in presence of surfactant
Solubility plays an important role in dissolution and absorption of drug. Benzoic acid has less solubility in aqueous media. The aim of present study was to study the effect of solubility enhancing agents at room tempera...
Evaluation of post operative healing response and patient comfort with two periodontal dressings- ResoPac and CoePak following periodontal flap surgery- A comparative clinical study.
Aim: to assess the patient comfort early wound healing with a periodontal dressing in patients who underwent periodontal flap surgeries. Materials and methods: A split mouth randomized comparative clinical study was cond...
The Role and Significance of C – Reactive Protein in Neonatal Sepsis: A Clinical Investigation
OBJECTIVE: To evaluate the role of CRP in the management of neonatal sepsis in a NICU setting where resources for diagnosis and monitoring prognosis is minimal. METHODOLOGY: The study was conducted at Dr. B.R. Ambedkar...
Standardization of the Standards: A Novel Idea in Clinical Biochemistry Review with Special Reference to Developing Countries
Objective: The principle of Physical Chemistry applies equally to the metabolic reactions or activities. The proportionality of the law of mass action of reactants and products indicates a linear decrease in the values,...