Identification of Biomarker Change in Spina Bifida by Meta-analysis on Reference Expression Database
Journal Title: Journal of Neurological Sciences-Turkish - Year 2008, Vol 25, Issue 1
Abstract
Spina bifida is a well-known congenital neurological defect. The epidemiological investigation of spina bifida, has a long history. Genetic, nutritional and teratogenic mechanisms have been implicated in the pathogenesis of spina bifida. In this work, the author used advanced metabolomics technique, meta-analysis on reference expression database to identify of biomarker change in spina bifida. The first biomarker search for Homo sapiens neurological system showed many relating biomarkers. After simulating for down regulation and up regulation, the variation in expression level of each identified biomarker can be seen.
Authors and Affiliations
Viroj WIWANITKIT
Keywords
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