Identification of Dentine Sialophosphoprotein In Gingival Crevicular Fluid To Assess Root Resorption Using Three Piece Base Arch
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 1
Abstract
Introduction: Apical root resorption is a common side effect of orthodontic treatment. Intrusion is suggested as a possible cause of root resorption affecting the prognosis of the patient. Diagnosis is usually done by radiographs. Dentine sialophosphoprotein (DSPP), a non-collagenous protein is released into gingival crevicular fluid during active root resorption. This study is aimed to identify the role of DSPP in root resorption during orthodontic intrusion using three piece base arch. Materials and method: GCF was collected from permanent maxillary central and lateral incisors of 10 control subjects with no history of orthodontic treatment and 10 experimental subjects before intrusion and 2 months after intrusion. DSPP was measured in GCF using ELISA method. Results: Statistical analysis showed there was highly significant increase in DSPP levels after 2 months of intrusion. Low levels of DSPP were detected in control subjects. There was no statistically significant difference between central and lateral incisors for the presence of DSPP in all groups. Conclusion: DSPP was present in GCF in increased levels in subjects undergoing intrusion with three piece intrusion base arch. DSPP can be considered as a biomarker for root resorption. It helps in monitoring root resorption during orthodontic treatment especially during intrusion.
Authors and Affiliations
Uma HL MDS, Nausheer Ahmed MDS
Keywords
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- EP ID EP574868
- DOI 10.9790/0853-1701015663.
- Views 68
- Downloads 0
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