Identification of insilico drugs and drug docking studies on hypothyroidism and inferility disorders in human
Journal Title: International Journal of Novel Trends in Pharmaceutical Sciences - Year 2015, Vol 5, Issue 3
Abstract
Hypothyroidism is a common endocrine disorder in which the thyroid gland does not produce sufficient thyroid hormone. It can cause a number of symptoms, such as tiredness, poor ability to tolerate cold, and weight gain. In this insilico research, we identified protein target drugs have significant role in treating hypothyroidism and associated female and male infertility disorders. The designed de novo drugs show higher binding affinities when compared to the existing drugs. Hence by way of this project we discover de novo drugs which act as potential therapeutic agents in controlling Hypothyroidism.
Authors and Affiliations
Anusha CS , Halidha Z , Radha T , Balaji M
Keywords
Related Articles
- EP ID EP112696
- DOI -
- Views 99
- Downloads 0
Insilco Homology modeling for Vitellogenin protein of fiddler crab (Uca princeps) using Bioinformatics tools
A fiddler crab, sometimes known as a calling crab, may be any of approximately 94 species of semi-terrestrial marine crabs which make up the genus Uca. As members of the family Ocypodidae, fiddler crabs are most closely...
In-vitro evaluation of timolol maleate matrix tablets formulated with different polymers and ratios
The purpose of the present study was to prepare and characterize twice-daily sustained-release matrix tablets of timolol maleate (TM) using different concentrations of natural, synthetic and semi-synthetic polymers. The...
Lung Cancer: A Better Rational Drug Designing, Docking and Predicting the Efficacy of Drugs
Understanding the role of bio molecular dynamics in cellular processes leading to human diseases and the ability to rationally manipulate these processes is of fundamental importance in scientific research. Lung cancer o...
Climate change prediction and software tool and database development using JAVA Programming Language
Indian media can contribute to increased awareness of climate change and related issues. A qualitative analysis of some mainstream Indian newspapers (particularly opinion and editorial pieces) during the release of the I...
In-Silico Molecular Docking Analysis of Cancer Biomarkers with Bioactive Compounds of Tribulus terrestris
Currently, in the research scenario for cancer, the identification of anti-cancer drugs using immuno-modulatory proteins and other molecular agents to initiate apoptosis in cancer cells and to inhibit the signalling path...