IgE antibodies in toxoplasmosis
Journal Title: Advances in Hygiene and Experimental Medicine - Year 2014, Vol 68, Issue
Abstract
Toxoplasmosis is a worldwide infection caused by the intracellular parasite Toxoplasma gondii. At least a third of the world human population is infected with the parasite, making it one of the most successful parasitic infections. Primary maternal infection may cause health-threatening sequelae for the fetus, or even cause death of the uterus. Reactivation of a latent infection in immune deficiency conditions such as AIDS and organ transplantation can cause fatal toxoplasmic encephalitis. Toxoplasmosis is a major cause of chorioretinitis, especially in individuals with impaired immune systems. In the acute phase, directly after invading the body, T. gondii begins to multiply rapidly. In the majority of cases acquired toxoplasmosis is asymptomatic. In the second week of infection, specific IgM antibodies are present in the blood. IgE antibodies appear at the same time, slightly preceding specific IgA antibodies. The concentration of IgE can be one of the parameters used for diagnosing an infection with T. gondii. Laboratory diagnosis, i.e. IgE and serologic assays, plays the main role in the diagnosis of congenital infection and assists in the confirmatory diagnosis of toxoplasmic encephalitis and ocular toxoplasmosis. This article is a review of IgE in toxoplasmosis.
Authors and Affiliations
Joanna Matowicka-Karna, Halina Kemona
Aktywność N-acetylo-β-D-heksozoaminidazy i jej izoenzymów A i B w nowotworach
Wczesne wykrycie choroby nowotworowej sprawia problemy nie tylko w Polsce, lecz i na całym świecie, dlatego wielu badaczy poszukuje ciągle swoistych i czułych markerów dla wczesnego rozpoznania określonego nowotworu. Pe...
Wpływ związków polifenolowych na zahamowanie immunosupresyjnego działania promieniowania UV na skórę
Immunoregulatory properties of Hsp70
Heat shock proteins 70 (Hsp70) play an important role in maintaining cellular homeostasis. As molecular chaperones, Hsp70 are responsible for proper folding of newly synthesized polypeptides and refolding of misfolded an...
Okołoporodowe źródła komórek macierzystych
Komórki macierzyste są jednym z odkryć medycyny i biologii wywołującym tyle samo nadziei w terapii, co kontrowersji natury etycznej i medycznej. Badania nad nimi zapoczątkowane już na początku XX w. wciąż dostarczają cor...
Dysregulation of the mTOR signaling pathway in the pathogenesis of autism spectrum disorders
Mammalian target of rapamycin (mTor) plays multiple role in central nervous system and is involved in regulation of cell viability, differentiation, transcription, translation, protein degradation, actin cytoskeletal org...