IgG Avidity: an Important Serologic Marker for the Diagnosis of Tick-Borne Encephalitis Virus Infection
Journal Title: Polish Journal of Microbiology - Year 2016, Vol 65, Issue 1
Abstract
A total of 52 serum sles from patients with symptoms suggestive of tick-borne encephalitis virus (TBEV) infection and positive IgM and/or IgG antibodies were tested for IgG avidity. Acute/recent TBEV infection was confirmed by low/borderline avidity index (AI) in 94.8% IgM positive/IgG positive sles, while in 5.2% high AI was found indicating persisting IgM antibodies. Majority of IgM negative/IgG positive sles (78.6%) showed high AI consistent with past TBEV infection. However, in 21.3% patients without measurable IgM antibodies current/recent infection was confirmed by AI. IgG avidity represents an additional serologic marker that improves diagnosis of TBEV, especially in cases of atypical antibody response.
Authors and Affiliations
Tatjana Vilibic-Cavlek, Ljubo Barbic, Vladimir Stevanovic, Goranka Petrovic, Gordana Mlinaric-Galinovic
Keywords
Related Articles
- EP ID EP81102
- DOI -
- Views 99
- Downloads 0
Recombinant MAG1 Protein of Toxoplasma gondii as a Diagnostic Antigen
The aim of this study was to evaluate the potential diagnostic usefulness of the full-length recombinant <em>Toxoplasma gondii</em> MAG1 protein by determining the levels of specific IgM and I...
Characterisation of Antimicrobial Properties of Extracts of Selected Medicinal Plants
The scope of the experiments included analysis of the antimicrobial activity of ethanolic, methanolic and aqueous extracts against bacterial and fungal cultures and determination of the minimum inhibitory concentration o...
MALDI-TOF MS Detection of Endophytic Bacteria Associated with Great Nettle (Urtica dioica L.), Grown in Algeria
Any plant with a vascular system has a specific endophytic microflora. The identification of bacteria is essential in plant pathology. Although identification methods are effective, they are costly and time consuming. Th...
Physiological Effects of Whey- and Milk-Based Probiotic Yogurt in Rats
In an in vitro experiment commercially available probiotic products were tested for the survival of bacteria under conditions of simulated human digestion either when used alone or mixed into yogurt. In the in vivo exper...
Participation of TP53 and Bcl-2 proteins in gastric carcinomas associated with [i]Helicobacter pylori[/i] or Epstein-Barr virus (EBV)
In the presented studies p53 and bcl-2 proteins expression were evaluated in samples of gastric carcinomas in patients with [i]Helicobacter pylori[/i] or EBV or without [i]H. pylori[/i]/EBV infection. The studies w...