Immune Paralysis and the Spontaneous Remission of Cancer
Journal Title: International Journal of Cancer and Clinical Research - Year 2017, Vol 4, Issue 2
Abstract
Once a malignant growth grows past a certain size immune tolerance rather than immune sensitization occurs possibly due to the slow tumor growth. As the malignant grows larger some branches of the immune system (adoptive immunity) become protective of it, while other branches of the immune system oppose its growth.
Angiogenesis Inhibitor Induced Thromboembolism in Cancer Patients
Therapy with Angiogenesis Inhibitors (AIs) is a newer targeted approach in treating cancers. It gained popularity in the past decade because of better outcomes and fewer side effects when compared to conventional chemoth...
Radiolabeled APIs for the Conduct of Human ADME Studies of Oncology Compounds
Human ADME (Absorption, Distribution, Metabolism, and Excretion) studies of new chemical entities are an important part of the drug development process. These studies are normally performed by using a radioactive tracer...
Bioactive Peptides from Legumes as Anticancer Therapeutic Agents
Food proteins are a source of nutraceutical and bioactive peptides that promote health and prevent diseases. Legume seed proteins have been widely studied to produce peptides (protein fragments) with a diversity of biolo...
The Role of Notch Signaling in Liver Diseases: Contribution to Development and Cancer
Liver tissue consists of several types of cells such as hepatocytes, endothelial cells, stellate cells, cholangiocytes, and immune cells, all with essential functions. The liver plays an important role in metabolism beca...
Physiological Effort in Submaximal Fitness Tests Predicts Weight Loss in Overweight and Obese Men with Prostate Cancer in a Weight Loss Trial
Background Obesity and weight gain after the diagnosis of prostate cancer are associated with an increased risk of prostate cancer recurrence and mortality; individualized plans to help prostate cancer survivors maintain...