Immuno-Pathological Profile Of Lesions On Prostate And Prostate Specific Antigen(Psa) Levels Of Prostatic Cancer.
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2019, Vol 2, Issue 1
Abstract
Background: Benign prostatic hyperplasia and adenocarcinoma are common diseases that account for considerable morbidity and mortality of ageing population. In cancer related deaths in men, the prostatic cancer is the second most common to lung cancer. To assess the morphological spectrum of lesions of prostate and serum PSA levels. Materials And Methods: The Retrospective study included a total of 62 samples of different prostatic lesions ,in the age range of 42 to 78 years, over a period of 1 year from May 2015 to July 2016. All the lesions were graded into non-neoplastic and neoplastic lesions. The histological data and serum PSA levels obtained were analyzed and compared with other similar studies.Results : Non neoplastic lesions were common in this study with Nodular hyperplasia(89%) with 52% associated with prostatitis. Among the neoplastic lesions adenocarcinoma occurred in 6% and urothelial carcinoma in 4.8%. Adenocarcinoma and PSA shows good correlation with final diagnosis(p value<0.05).Conclusion: Serum PSA was a good tool for screening carcinoma prostate; however biopsy is essential for diagnosis. More studies are required in relation to benign mimickers.
Authors and Affiliations
Dr. Jenifer Lancy
Keywords
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