Immuno-Pathological Profile Of Lesions On Prostate And Prostate Specific Antigen(Psa) Levels Of Prostatic Cancer.
Journal Title: International Journal of Medical Science And Advanced Clinical Research (IJMACR) - Year 2019, Vol 2, Issue 1
Abstract
Background: Benign prostatic hyperplasia and adenocarcinoma are common diseases that account for considerable morbidity and mortality of ageing population. In cancer related deaths in men, the prostatic cancer is the second most common to lung cancer. To assess the morphological spectrum of lesions of prostate and serum PSA levels. Materials And Methods: The Retrospective study included a total of 62 samples of different prostatic lesions ,in the age range of 42 to 78 years, over a period of 1 year from May 2015 to July 2016. All the lesions were graded into non-neoplastic and neoplastic lesions. The histological data and serum PSA levels obtained were analyzed and compared with other similar studies.Results : Non neoplastic lesions were common in this study with Nodular hyperplasia(89%) with 52% associated with prostatitis. Among the neoplastic lesions adenocarcinoma occurred in 6% and urothelial carcinoma in 4.8%. Adenocarcinoma and PSA shows good correlation with final diagnosis(p value<0.05).Conclusion: Serum PSA was a good tool for screening carcinoma prostate; however biopsy is essential for diagnosis. More studies are required in relation to benign mimickers.
Authors and Affiliations
Dr. Jenifer Lancy
A Prospective, Double Blind, Randomized Clinical Study on Effect of Oral Clonidine Premedication on the Induction Dose of Intravenous Thiopentone Sodium
Background: Preanaesthetic medication significantly modulates intraoperative requirement of anaesthetic agents such as the i.v. anaesthetic Thiopentone sodium. Objectives: A prospective, randomised, double blind, was don...
A Comparative Study of Dexmedetomidine As Adjuvants To Intrathecal Heavy Bupivacaine (0.5%) For Lower Abdominal Surgeries.
Introduction: Several adjuncts like adrenaline,opioids and alpha-2 adrenergic agonists are being used with local anaesthetics intrathecally for prolongation of intra-operative and post...
A Retrospective Study To Determine Patients’ Satisfaction With Fixed Dental Prostheses Provided during the Period 2015 – 2018 in the dental clinic at IBN SINA National college for medical studies, Jeddah, Saudi Arabia.
Background: The Assessment of prosthetic treatment provided is essential to determine oral health care needs in a systematic manner and to gather the information required to bring about change benef...
Prevention of Hypotension with a Single Prophylactic Dose of Ephedrine (9mg) In Patients during Spinal Anaesthesia
Objective: The aim of the study was to assess the efficacy of single prophylactic dose (9mg) of ephedrine given to prevent hypotension in patients during spinal anaesthesia. This study was conducted at Anaesthesia Depart...
A Comparative Study Between 0.5% Bupivacaine With Clonidine And 0.5% Bupivacaine Alone For Supraclavicular Brachial Plexus Block In Upper Limb Surgeries
Background:Supraclavicular brachial plexus block provides safe, effective, low cost anaesthesia with excellent post-operative analgesia. The current study was an attempt to compare Bup...