IMMUNOLOGYCAL APPROACH TO THE DIAGNOSIS OF AUTISM
Journal Title: Journal of Special Education and Rehabilitation - Year 2005, Vol 6, Issue 1
Abstract
To date, neurotransmitter and immune abnormalities in autism are the only consistently documented findings other than neurobehavioral symptoms. Reciprocal communication between two major adaptive systems of human organism, the CNS and the immune system, is sustained via multiple pathways and is mediated by neurotransmitters, hormones, cytokines, chemokines, and corresponding cell receptors. Evidence for a dialogue between them has emerged as a universal concept of the neuroimmune regulation of homeostasis. In the paper we propose several plausible scenarios of how defects in either system may affect neuroimmune communications and lead to the pathology, as well as immunodiagnostic panels for recognition of immunopathological changes in people with autism in the Republic of Macedonia.
Authors and Affiliations
Mirko Zh. SPIROSKI| Faculty of Medicine Institute of Immunobiology and Human Genetics Skopje, Macedonia
Keywords
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