IMMUNOPROPHYLAXIS OF PSEUDOMONOSIS: ACHIEVEMENTS AND PERSPECTIVES
Journal Title: Annals of Mechnikov Institute - Year 2018, Vol 0, Issue 2
Abstract
The review article presents a retrospective analysis of attempts to develop effective vaccines for pseudomonas prophylaxis. P. aeruginosa vaccine has been sought for 40 years; however it is still not available. The increased understanding of P. aeruginosa pathogenesis and its virulence factors supported the recognition of potential immunogens and passive immunotherapy that could be used for the development of an effective vaccine. These immunogens are situated in structural components such as lipolysaccharides, pili, flagella, outer membrane proteins or are part of secreted products such as proteases, exotoxins and mucoid exopolysaccharides. There have been significant advances in later years; nonetheless there is clear need for additional basic research to further increase the understanding of those elements of immune response to P. aeruginosa.
Authors and Affiliations
N. I. , Gorodnitskaya, L. N. , Gabysheva, S. A. , Derkach, A. V. Martynov
Keywords
Related Articles
- EP ID EP612788
- DOI 10.5281/zenodo.1303954
- Views 242
- Downloads 0
INFORMATIONAL AND EDUCATIONAL INTERNET APPLICATION, AS A FORM OF PHARMACEUTICAL INTERVENTION IN THE MEDICATION-TAKING BEHAVIOR OF THE APPLICANTS OF HIGHER MEDICAL EDUCATION
Aim: to work out the informational and educational model of pharmaceutical intervention in the medication-taking behavior of the applicants of higher medical education on the basis of modern information technologies to p...
DEFINITION OF MATHEMATICAL MODELS OF SHOTS DISTANCE DETERMINATION USING BIOLOGICAL IMITATORS OF HUMAN TISSUES
Introduction. One of the most common tasks in expert practice which is solved during investigation of almost all the facts of firearms usage is determination of shots distance. To realize this aim laboratory diagnostic m...
IMBALANCE OF IgG SUBCLASSES IN PRESCHOOL CHILDREN WITH A DIFFERENT TYPE OF VACCINE RESPONSE TO MMR
Introduction. The only way to protect children against measles, mups and rubella viruses (MMR) is vaccination. However, among vaccinated individuals there are always people who react poorly to vaccine preparations until...
PHAGOCYTAL ACTIVITY OF NEUTROPHILES AND PERIPHERAL BLOOD MONOCYTES IN PATIENTS WITH HBV INFECTION
Introduction. Treatment of HBV infection is one of the global problems of modern medicine, which is confirmed by the extraordinary prevalence and high mortality from this disease. Elimination of acute hepatitis B (GHB) f...
A STUDY OF ANTIMICROBIAL ACTIVITY OF FOAM-WASHING AGENT SPECIMENS AT ACIDIC PH VALUES
Introduction. It is well-known that any parapharmaceutical substance, in particular, foam-washing agents comprising water in combination with detergents, extracts, water-soluble vitamins, viscosity regulators, pH, etc.,...