Immunotherapy in Prostate Cancer
Journal Title: The Bulletin of Urooncology - Year 2009, Vol 18, Issue 2
Abstract
In recent years, immunotherapy has become an important treatment alternative in the treatment of many cancers. Research on immunotherapy in prostate cancer has been accelerated by obtaining Food and Drug Administration (FDA) approval of sipuleucel-T for asymptomatic or minimal symptomatic metastatic castration-resistant prostate cancer (CRPC). Despite all these developments, the patients in whom these agents should be used, sequential use and combination strategies remain unclear. In this review, mechanisms of action and survival outcomes of different immunotherapeutic agents and therapeutic cancer vaccines in mCRPC are discussed.
Authors and Affiliations
Deniz Bolat MD, Ayfer Haydaroğlu,
Keywords
Related Articles
- EP ID EP48741
- DOI 10.4274/uob.galenos.2018.1142
- Views 270
- Downloads 0
Impact of Neoadjuvant Sunitinib Treatment on Tumour Thrombi in the Inferior Vena Cava in Metastatic Renal Cell Carcinoma
The authors report cases of metastatic renal cell carcinoma with level III-IV tumour thrombi in the inferior vena cava (IVC). Cases were treated with three courses of neoadjuvant sunitinib to reduce the thrombus level be...
Risk of Neoplastic Squall Downstream Cytokine Storm of COVID-19 in Male Patients
No summary
Risk Factors Affecting Complications Due to Prostate Biopsy
Objective: Currently, transrectal ultrasound (TRUS) guided prostate biopsy is the standard method used for prostate cancer detection. In the last decade, hospitalization due to complications has increased, especially due...
Association of Preoperative De Ritis Ratio (Aspartate Amino Transferase/Alanine Amino Transferase) and Tumour Histology in Patients with Primary Bladder Cancer
Objective: De Ritis ratio, defined as the ratio of serum aspartate amino transferase (AST) and alanine amino transferase (ALT), has been demonstrated to be an independent prognostic marker in bladder cancer (BC) patients...
Renal Angiomyolipoma: A Clinicopathological Study of Seven Cases and Review of the Literature
Objective: Renal angiomyolipomas (AMLs) are mesenchymal kidney tumours that have triphasic histology. This study aimed to present the clinical, pathological and immunohistochemical features of seven AML cases along with...