IMPORTANCE OF HISTOPATHOLOGY OF INTUSSUSCEPTION AND EVALUATION OF CAUSE OF INTUSSUSCEPTION IN INFANTS AND CHILDREN- A 4 YEARS STUDY

Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 40

Abstract

BACKGROUND In early childhood, the commonest cause of bowel obstruction is intussusception and is one of the common abdominal emergencies in children. Early diagnosis helps to reduce mortality and morbidity. The objective of the study is to assess the usefulness/ efficacy of histopathology in intussusceptions. Clinical and radiological features are useful, but histopathology is the final diagnosis which helps in identifying the aetiology of intussusception. Accurate diagnosis is essential as treatment is variable, as histopathological diagnosis of intussusceptions varies from benign to malignant lesions. MATERIALS AND METHODS The study was a retrospective descriptive study of 4 years duration and included 60 cases. The gross specimens and histopathological slides of all the surgically resected specimens of intestines with intussusception at a tertiary paediatric referral centre were studied in detail with clinical and radiological correlation. RESULTS In 4 years study period, from June 2009 to June 2013, 60 cases which were surgically irreducible were resected and sent to histopathology department. The diagnosis was established by barium enema, x-rays or at laparotomy. There were 60 children, age ranging from 15 days to 13 years. Among these children 40 were male and 20 were female, ratio being 2: 1. The age group most commonly affected were less than 1 year. The classic triad of abdominal pain, vomiting and rectal bleeding was encountered in 49 patients. Out of 60 cases, aetiology of intussusception included Meckel’s diverticulum 30 (50%), submucosal lymphoid hyperplasia 19 (31.9%), inflamed appendix 8 (13.3%), submucosal haematoma 1 (1.6%), polyp 1 (1.6%) and malignant lymphoma 1 (1.6%). The ileocecal area was the site most commonly involved (82%). Hypertrophic Peyer’s patches of the terminal ileum being responsible for idiopathic intussusception in the ileocolic area. There were 59 benign developmental lesions and 1 malignant tumour. Enlargement of the mesenteric lymph nodes occurred in 35% cases.

Authors and Affiliations

K. Geetha, O. H. Radhika Krishna, Srinivas Reddy P, Ramesh Reddy Kota

Keywords

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  • EP ID EP548226
  • DOI 10.14260/jemds/2018/976
  • Views 75
  • Downloads 0

How To Cite

K. Geetha, O. H. Radhika Krishna, Srinivas Reddy P, Ramesh Reddy Kota (2018). IMPORTANCE OF HISTOPATHOLOGY OF INTUSSUSCEPTION AND EVALUATION OF CAUSE OF INTUSSUSCEPTION IN INFANTS AND CHILDREN- A 4 YEARS STUDY. Journal of Evolution of Medical and Dental Sciences, 7(40), 4377-4380. https://europub.co.uk/articles/-A-548226