IMPORTANT OF SPIRULINA PLATENSIS TO RESTRAIN SULFUR TOXICITY IN SEA BASS DICENTRARCHUS LABRAX
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2018, Vol 5, Issue 2
Abstract
Background: Because of the potential antioxidant, anti-inflammatory, and immune-modulating properties of Spirulina platensis, there is an increased interest in its potential role in the prevention and control of sulfur toxicity in sea bass Dicentrarchus labrax. Objective: This study investigated the effects of sodium sulphate on sea bass (Dicentrarchus labrax) and protection effect of Spirulina platensis. Material and methods: A total of 260 sea bass exposed to 1/10 dose of sodium sulphate 96hr-LC50 (5.8 mg/L) and study the changes in antioxidant enzyme activities of serum. In addition to, study the amelioration of sodium sulphate toxicity by addition of S. platensis to the ration of exposed fish by the rate of 1%. Results: The results showed that the sodium sulphate at dose of 5.8 mg/L the level of SOD; CAT; GPx and TAC activity in the serum of sea bass were decreased. The SOD; CAT; GPx and TAC activity in sodium sulphate exposed group was found lower than the S. platensis supplemented groups. Exposure of sea bass to sodium sulphate for 8th weeks resulted in significant changes in mRNA abundance for a limited subset of the analyzed of hepatic sea bream genes. GSR; SOD and GPXs mRNA levels decrease significantly upon incubation with sodium sulphate, in liver, irrespectively to the length of the treatment, whereas the corresponding levels of sea bass feed with 1% S. platensis were indistinguishable from controls. Discussion and conclusion: S. platensis ameliorated the adverse biochemical effect of sodium sulphate toxicity in sea bass, likely by increasing and improving the antioxidant status.
Authors and Affiliations
Dr. Rayed H. Khalil
Keywords
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