IMPROVEMENT OF “LACTULOSE-MANNITOL RECOVERY RATIO TEST” OF INTESTINAL ABSORPTION BY LC-MS\MS
Journal Title: International Journal of Medical Laboratory Research - Year 2019, Vol 4, Issue 2
Abstract
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has seen enormous growth in clinical laboratories during the last decades due to the fact that it offers analytical specificity superior to that of immunoassays or conventional high performance liquid chromatography. Then, most chemicals and metabolites are now assayed by LC-MS/MS. The “Lactulose\Mannitol recovery ratio (LAMA test)” is a non-invasive gastrointestinal test for the assessment of intestinal absorption and barrier function of the bowel. This article describes an optimized LC-MS/MS method used for the determination of these two sugars, characterized by rapidity, sensitivity, and easy automation.
EVALUATION AND COMPARISON OF RAPID CARD TEST WITH IgM ELISA FOR DIAGNOSIS OF SCRUB TYPHUS: A STUDY DONE IN PERIPHERAL ZONAL HOSPITAL OF HIMACHAL PRADESH (INDIA)
Background: Scrub typhus is a tropical febrile zoonotic disease caused by Orientiatsutsugamushi of the rickettsial family. Clinical diagnosis of scrub typhus is often difficult because of similarity of symptoms to other...
TYPES OF PRE-ANALYTICAL ERRORS IN CLINICAL HEMATOLOGY LABORATORY
Background: Since, clinical laboratory results play an important role in patient’s diagnosis, investigation and treatment. Thus, errors with laboratory tests might lead to inappropriate medical decision-making. Such erro...
QUALITATIVE AND QUANTITATIVE ANALYSIS OF BILIARY CALCULI IN A TERTIARY CARE HOSPITAL
Background :- Gallstone disease remains a serious health concern for human beings, affecting millions of people throughout the world. Material and method:- The cross sectional study was conducted in department of Biochem...
DETERMINATION OF LC50 OF PHENOLIC COMPOUNDS (PHENOL & M-CRESOL) FOR A FISH, LABEO ROHITA
Water pollution has become a global problem as various pollutants like heavy metals and toxic chemicals are discharged without prior treatment into the water. With the development of industrial production, a large volume...
A DISCUSSION ON SUTURE AND LIGATURE
The aim of the study was to give information on properties of suture and ligature materials in order to assist surgeons in their selection of adequate sutures for specific surgical applications. The essential requirement...