ІМУНОГІСТОХІМІЧНЕ ДОСЛІДЖЕННЯ РЕЦЕПТОРНОЇ АКТИВНОСТІ ЕУ- ТА ЕКТОПІЧНОГО ЕНДОМЕТРІЮ ПРИ АДЕНОМІОЗІ У ПОЄДНАННІ З ЕНДОМНЕРІОЇДНОЮ КАРЦИНОМОЮ ЕНДОМЕТРІЮ
Journal Title: World Science - Year 2018, Vol 5, Issue 6
Abstract
The article is devoted to the role of estrogen (ER) and progesterone (PR) receptors in the pathogenesis of adenomyosis (AМ) in the presence of the endometrioid carcinoma of uterine (ECU) in postmenopausal women. The research material included the uterus removed from 17 patients (52-74 years old) with AМ and ECU. An іmmunohistological study was performed to determine the state of the ER and PR. The study of the eu- and ectopic endometrium receptor apparatus revealed the presence of both in the epithelial cells and in the stromal cells, indicating the hormonal dependence of AМ and the key role of steroid hormones in the development of intraocular endometriosis in postmenopausal women. An increased level of ER and PR activity was detected respectively to the improvement of differentiation degree of the eutopic endometrium epithelial cells. It has been established that limited estrogenic and expressed progesterone receptor activities are pathogenetically significant for AМ.
Authors and Affiliations
Г. Ю. Гончаренко
Keywords
Related Articles
- EP ID EP331306
- DOI 10.31435/rsglobal_ws/12062018/5854
- Views 118
- Downloads 0
РОЛЬ ПАРЛАМЕНТА РЕСПУБЛИКИ КАЗАХСТАН В МЕЖДУНАРОДНОЙ И МЕЖПАРЛАМЕНТСКОЙ ДЕЯТЕЛЬНОСТИ
This article looks at the activities of the Parliament of the Republic of Kazakhstan in sphere of interparliamentary cooperation.
ПРОБЛЕМЫ РАЗВИТИЯ БОЛОНСКОЙ СИСТЕМЫ ОБРАЗОВАНИЯ В АЗЕРБАЙДЖАНЕ
The article discusses the process of introducing the Bologna system in Azerbaijan and the problems associated with it. The development of the Bologna process is largely predetermined by the conditions of the General refo...
CYTOGENETIC ACTIVITY OF POLLUTANTS BY HEAVY METAL CAUSED BY EMISSIONS OF INDUSTRIAL ENTERPRISES
A cytogenetic analysis of meristem cells of T. aestivum L. of primary rootlets, affected by soil heavy metal (HM) contamination in the industrial zones of instrument engineering companies in Poltava city, a garbage proce...
КОМПЛЕКСНЫЙ ПОДХОД К ИСПОЛЬЗОВАНИЮ ИНФОРМАЦИОННЫХ ТЕХНОЛОГИЙ В СИСТЕМЕ ЗДРАВООХРАНЕНИЯ
Currently, innovation in healthcare in general and hospitals in particular, is characterized by the blurring of priorities, low level of innovative potential even in the leading universities of the Russian Federation, wi...
РОЗРОБКА МОДЕЛІ ВИНИКНЕННЯ КРИТИЧНИХ ДОРОЖНЬО-ТРАНСПОРТНИХ СИТУАЦІЙ
The article describes an algorithm for the study through simulation parameters danger of traffic, which allowed proposing the introduction of such new methods as the quantification and identification of traffic dangers f...