IN VITRO ACTIVITY OF COLISTIN AGAINST MULTIDRUG RESISTANT GRAM NEGATIVE BACILLI (MDR GNB) ISOLATED FROM VARIOUS CLINICAL SPECIMENS

Journal Title: IJSR-International Journal Of Scientific Research - Year 2018, Vol 8, Issue 4

Abstract

Introduction: Currently colistin is increasingly being used against multidrug resistant gram negative bacteria which include Pseudomonas aeruginosa,,Acinetobacter baumanii, Escherichia coli, Klebsiella pneumoniae & Salmonella enterica. [1] Colistin resistant organisms are reported in various parts of world. Methods: Total 200 MDR GNB isolates were included in the study & tested for their susceptibility to colistin by Kirby Bauer Disc Diffusion Test. Results: Isolates consisted of 64 Escherichia coli,45 Pseudomonas aeruginosa, 44 Klebsiella pneumoniae,32 Citrobacter koseri,13 Acinetobacter baumanii & 2 Proteus mirabilis. Of these, 69 (34.5%) were resistant to Colistin. Colistin resistance in highest number was detected in Escherichia coli isolates obtained from various samples. Conclusion: As colistin resistance is emerging rapidly, measures are necessary to restrict indiscriminate use of antimicrobials & to adhere strictly to the hospital antibiotic policy. It is also the need of an hour that newer antimicrobials get discovered soon to tackle such MDR microorganisms.

Authors and Affiliations

Dr. Ketaki Vyankatesh Kulkarni, Dr. Sandhya S. Kulkarni, Dr. Niranjan Pathak

Keywords

Related Articles

A CLINICAL STUDY ON LENS INDUCED GLAUCOMA IN A TERTIARY CARE HOSPITAL

To determine the clinical profile and outcome in cases of lens-induced glaucoma (LIG).A retrospective analysis of 31 cases with LIG was evaluated over a period of one year at a rural tertiary care hospital. The cases ran...

A STUDY OF CLINICAL PROFILE AND OUTCOME IN ACUTE VIRAL HEPATITIS E IN RAIPUR CG

Acute viral hepatitisE (HEV) is generally mild and self-limiting and resolves within six weeks, with no chronic sequelae. Pregnant women are at increased risk with the risk increasing as the pregnancy progresses near ter...

REPRODUCTIVE HEALTH PROFILE OF WOMEN ATTENDING RTI/STI CAMP IN A RURAL AREA OF NORTHERN DISTRICT OF KERALA STATE

Background; Reproductive Tract Infection/Sexually Transmitted Infection is a major public health issues among women especially those of low socioeconomic status. Early diagnosis and treatment prevents serious complicatio...

HOLT-ORAM SYNDROME RARE HAND-HEART DISORDER

Back ground: Holt-Oram is rare autosomal disorder, clinically characterised by congenital cardiac defects and morphological abnormalities of the upper limbs. Case characteristics:10 days old neonate born to first degree...

RISK STRATIFICATION USING APPENDICITIS INFLAMMATORY RESPONSE SCORE, A USEFUL TOOL TO REDUCE NEGATIVE APPENDICECTOMY RATE : OUR EXPERIENCE

Background: Acute appendicitis is mostly considered a clinical diagnosis and many surgeons resort to clinical judgement for deciding its management. Such cases often pose a diagnostic dilemma and result in significant ne...

Download PDF file
  • EP ID EP382568
  • DOI -
  • Views 66
  • Downloads 0

How To Cite

Dr. Ketaki Vyankatesh Kulkarni, Dr. Sandhya S. Kulkarni, Dr. Niranjan Pathak (2018). IN VITRO ACTIVITY OF COLISTIN AGAINST MULTIDRUG RESISTANT GRAM NEGATIVE BACILLI (MDR GNB) ISOLATED FROM VARIOUS CLINICAL SPECIMENS. IJSR-International Journal Of Scientific Research, 8(4), 11-12. https://europub.co.uk/articles/-A-382568