In vitro Activity of Garlic (Allium sativum) on Some Pathogenic Fungi
Journal Title: European Journal of Medicinal Plants - Year 2014, Vol 4, Issue 10
Abstract
Aim: This study was conducted to investigate the in vitro antifungal activity of garlic (Allium sativum) on some pathogenic fungi. Study Design: This is a comparative evaluation report on garlic as an antifungal agent. Place and Duration: Department of mycology, Veterinary Research institute, between June-October 2013. Methodology: Samples of garlic were obtained from a local market. It was thoroughly, cleaned, peeled and pulverized. Aqueous and organic extracts of garlic were obtained by maceration and Soxhlet extractor apparatus. The methanol and petroleum ether extracts were tested against Candida albicans, Aspergillus, Curvularia and some Dermatophyte species using cup diffusion and agar incorporated methods. Diameter of Inhibition zones of growth were measured in millimeter (mm) and expressed as Mean ±SD. Results: The obtained results revealed that aqueous and petroleum ether extracts possess the stronger activity and a broader fungicidal spectrum against tested fungi compared to methanol extract. The study also showed that the dry coarsely- powdered garlic was found to be more potent to Candida albicans than the commercial Nystatin. Conclusion: The study demonstrated the potent activity of garlic against tested fungi which encourages its use as a suitable alternative drug for controlling fungal infections because it has far less risk of side-effects than most known antifungal drugs and it can be used indefinitely in quite large amounts. Therefore, adding garlic to food (raw) or crushing and swallowing raw cloves which are cheaper is recommended as a powerful anti-fungal agent. Further purification and formulation of the garlic would give a true antifungal activity comparable to standard antibiotics.
Authors and Affiliations
Elham Abdelbasit Suleiman, Wafa Ballal Abdallah
Keywords
Related Articles
- EP ID EP350279
- DOI 10.9734/EJMP/2014/10132
- Views 108
- Downloads 0
Comparative Study on the Phytochemical Compositions and Antihyperglycemic Potentials of the Leaves Extracts of Combretum paniculatum and Morinda morindoides
The phytocheimcal components and antihyperglycemic potential of methanol and ethanol leaves extracts of Combretum paniculatum Vent (Combretaceae) and Morinda morindoides (Baker) Milne-Redh (Rubiaceae) grown in Nigeria ha...
An Overview of Ethiopian Traditional Medicinal Plants Used for Cancer Treatment
Traditional medicine plays a significant role in the healthcare of the majority of the people in developing countries, including Ethiopia, and medicinal plants provide valuable contribution to this practice. Emerging evi...
Comparison of the Antioxidant Activity of Aromatic Medicinal Plants of Moroccan Origin
The purpose of this work is to appreciate different aromatic and medicinal plants from Morocco belonging to four different families, by chemical characterization and evaluation of their antioxidant activity. The reducing...
Infleunce of Nauclea latifolia Leaf Extracts on Some Haematological Parameters of Rats on Coconut Oil and Non-coconut Oil Meals
Aims: The haematological effects of Nauclea latifolia leaf extract on normal mature albino Wistar rats and normal mature hyperlipidemic rats were being investigated. Study Design: 55 albino rats weighing between 200 – 23...
Suppression of Inflammatory Mediators by the Ethanol Extract of Crotalaria verrucosa L. leaf – in vivo and in vitro Analysis
Objective: The present study demonstrated the potential of Crotalaria verrucosa L., a widely used medicinal plant of Bangladesh, ethanolic leaf extract in inhibiting the cascades of inflammation. Methods: Carrageenan in...